Split-dosed MiraLAX/Gatorade is an effective, safe, and tolerable option for bowel preparation in low-risk patients: a randomized controlled study

The American Journal of Gastroenterology
Jason B SamarasenaM Mazen Jamal

Abstract

MiraLAX with Gatorade is a low-volume bowel preparation regimen that has been used widely in community practice and is anecdotally better tolerated than Golytely. Despite its widespread use, there are little data on the efficacy and tolerability of this solution and no safety data in the literature. The primary aim of this study was to compare the efficacy, safety, and tolerability of single-dosed and split-dosed regimens of MiraLAX/Gatorade with Golytely for bowel preparation before colonoscopy. Adults presenting for outpatient colonoscopy were screened for enrollment into this single-blinded randomized controlled trial. Patients with severe cardiac or renal disease and patients with electrolyte abnormalities were excluded. Subjects were randomized into four groups: 4 l Golytely single-dosed (Go-Si), 4 l Golytely split-dosed (Go-Sp), 238 g MiraLAX in 64 oz of Gatorade single-dosed (Mlax-Si), and MiraLAX/Gatorade split-dosed (Mlax-Sp) groups. Laboratory data including complete blood count, comprehensive metabolic panel, and osmolality were collected before the day of bowel preparation and just before the start of colonoscopy. Subjects completed a survey assessing taste and tolerability of the solution. Colonoscopies were record...Continue Reading

References

Jul 24, 2002·The American Journal of Gastroenterology·Douglas K RexL Lisa Bratcher
Dec 21, 2002·The American Journal of Gastroenterology·Gavin C HarewoodL Joseph Melton
Jul 3, 2003·Gastrointestinal Endoscopy·Gavin C HarewoodPat de Garmo
Jul 11, 2006·Journal of Clinical Gastroenterology·Jerry NaglerMeredith Turetz
May 1, 2009·Nature Reviews. Gastroenterology & Hepatology·Kaitlin E Occhipinti, Jack A Di Palma
Jun 2, 2009·Gastrointestinal Endoscopy·Petar MamulaWilliam M Tierney
Jan 19, 2010·Digestive Diseases and Sciences·R Zackary UngerDouglas K Rex
Dec 1, 2010·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Michael HjelkremStephen A Harrison
Jan 5, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Frederick H Weber

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Citations

Mar 25, 2014·World Journal of Gastroenterology : WJG·Sanghoon Park, Yun Jeong Lim
Aug 20, 2014·The American Journal of Gastroenterology·Sameer SiddiqueMatthew L Bechtold
Dec 28, 2016·Scandinavian Journal of Gastroenterology·Seon-Young ParkJong-Sun Rew
Aug 19, 2015·Inflammatory Bowel Diseases·Min Chen, Bo Shen
Nov 30, 2018·Current Opinion in Gastroenterology·Parth J ParekhDavid A Johnson
Jul 16, 2013·Current Gastroenterology Reports·Stephen W Landreneau, Jack A Di Palma
Jan 28, 2014·Journal of Clinical Gastroenterology·Audrey H CalderwoodPaul C Schroy
Jun 4, 2014·World Journal of Gastrointestinal Endoscopy·David WidjajaBhavna Balar
Oct 1, 2019·Journal of Pediatric Gastroenterology and Nutrition·Parijat Ram TripathiAnshu Srivastava
Dec 20, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Isaac Seow-En, Francis Seow-Choen
Feb 8, 2019·The American Journal of Gastroenterology·Phillip GuChristopher V Almario
Dec 17, 2014·World Journal of Gastrointestinal Endoscopy·Hendrikus Jm Pullens, Peter D Siersema
Jul 19, 2018·World Journal of Gastroenterology : WJG·David KastenbergStuart Brogadir
Jan 9, 2019·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Ashish Kumar JhaKuldeep Sehrawat
Oct 8, 2014·The American Journal of Gastroenterology
Jan 1, 2018·Gastroenterology·Denis HadjiliadisUNKNOWN Cystic Fibrosis Colorectal Cancer Screening Task Force

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