Split-line pattern and histologic analysis of a human osteochondral plug graft

Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Brian M LeoDavid R Diduch

Abstract

The split-line pattern of collagen fibers in articular cartilage is oriented according to weight-bearing stresses. The importance of aligning the split-line pattern of articular cartilage in human osteochondral plug grafts relative to the surrounding cartilage has been proposed but not evaluated clinically. The purpose of this case report is to compare the articular split-line pattern with the histologic analysis of a specimen obtained from a patient who underwent an osteochondral plug transfer procedure with subsequent conversion to joint arthroplasty. The fresh osteochondral section obtained at total knee arthroplasty, including the area treated 18 months earlier with an osteochondral plug transfer, was fixed in formalin. Split-lines were demonstrated on the surface using a needle dipped in India ink. After decalcification and paraffin embedding, the specimen was sectioned and stained with Safranin O and fast green for histologic analysis. The split-line pattern of the anterior portion of the graft was oriented parallel to the resident cartilage; however, collagen orientation was divergent (approximately 30 degrees oblique) to the surrounding cartilage near the posterior portion of the graft. It was at this margin that furthe...Continue Reading

References

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Citations

Oct 27, 2006·The Journal of Orthopaedic and Sports Physical Therapy·Lajos BarthaLászló Hangody
Sep 16, 2006·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Gustav AndreisekDominik Weishaupt
Apr 11, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Mika E MononenRami K Korhonen
Oct 13, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·ShaoKuan ZhengFarid Badar
Apr 11, 2013·Computer Methods in Biomechanics and Biomedical Engineering·Mika E MononenRami K Korhonen
Nov 4, 2015·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Andrew B CampbellDavid C Flanigan

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