Spondylodiscitis caused by Mycobacterium xenopi

Archives of Orthopaedic and Trauma Surgery
R SobottkeP Eysel

Abstract

The infection with non-tuberculous mycobacterium correlates highly with immunodeficiency. Mycobacterium xenopi (M. xenopi) is most commonly isolated in the respiratory tract, as a cause of endogenous spondylodiscitis it occurs but rarely. Only seven such cases have been reported in literature. In this paper, we present the case of an about 28-year-old HIV-positive patient with a long history of back pain. MRI of the spinal column and Positron Emission Tomography with (18)F-fluorodeoxyglucose as a tracer (F18-FDG-PET) confirmed the suspected spondylodiscitis. After performing a CT-controlled abscess drainage the patient's condition improved. Because of the severe destruction of the spinal segment concerned and because of the epidural abscess formation a vertebrectomy of T10 and surgical debridement of the paravertebral soft tissue via thoracotomy became urgently necessary. The spine was stabilized by interposing a cage and an anterolateral monobar system. M. xenopi could be proven by PCR out of the intraoperative specimen. After operation and antituberculotic therapy there was a fast convalescence. Diagnostics, therapy, and clinical outcome are discussed.

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Citations

Aug 24, 2012·Der Orthopäde·V BullmannT Lange
Sep 23, 2009·Archives of Orthopaedic and Trauma Surgery·Rolf SobottkePeer Eysel
Jan 1, 2012·Journal of Community Hospital Internal Medicine Perspectives·Majd AlfreijatCarlton Sexton
Sep 1, 2011·Nuclear Medicine and Molecular Imaging·William Makis, Christopher Rush
Mar 13, 2012·Joint, Bone, Spine : Revue Du Rhumatisme·Jean-Hugues SalmonJean-Paul Eschard
May 25, 2010·International Journal of Antimicrobial Agents·Ghassan S SkafSouha S Kanj

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