Spontaneous baroreflex measures are unable to detect age-related impairments in cardiac baroreflex function during dynamic exercise in humans.

Experimental Physiology
James P FisherPaul J Fadel

Abstract

The dynamic relationship between 'spontaneous' fluctuations in arterial blood pressure (BP) and heart rate (HR) is increasingly being used to provide an estimate of resting cardiac baroreflex sensitivity. Given the ease of use and clinical utility, spontaneous methods are now also being used to examine cardiac baroreflex sensitivity in distinct subject groups during various laboratory stressors and tasks encountered during daily life, such as physical activity. However, the utility of such spontaneous measures to estimate cardiac baroreflex function during exercise remains unclear, particularly when comparing groups. Therefore, we tested the ability of spontaneous indices to detect age-related differences in cardiac baroreflex function during dynamic exercise. Beat-to-beat HR and BP were measured in eighteen healthy young subjects (24 +/- 1 years) and sixteen healthy middle-aged subjects (59 +/- 1 years) at rest and during steady-state leg cycling. Estimates of spontaneous cardiac baroreflex sensitivity using the sequence technique (G(SEQ)) and low-frequency transfer function gain (G(TF)) were compared with the operating point (G(OP)) and maximal gain (G(MAX)) of the full carotid-cardiac baroreflex function curve. At rest G(SEQ...Continue Reading

References

Sep 1, 1992·The American Journal of Physiology·T J EbertJ J Smith
Aug 1, 1991·Circulation·A MallianiS Cerutti
Oct 1, 1991·The American Journal of Physiology·J P SaulR J Cohen
Aug 1, 1988·Journal of the Autonomic Nervous System·M PaganiA Malliani
Jan 1, 1972·Cardiology·B B KentJ W Manning
Oct 1, 1971·Circulation Research·B GribbinR Peto
Sep 1, 1984·Journal of the Autonomic Nervous System·P ParkerD I McCloskey
Jan 1, 1982·Medicine and Science in Sports and Exercise·G A Borg
Jul 1, 1980·The Journal of Physiology·D L EckbergV L Roberts
Aug 1, 1995·Hypertension·M W ChapleauF M Abboud
Apr 1, 1995·The American Journal of Physiology·G ParatiG Mancia
Nov 1, 1994·Medicine and Science in Sports and Exercise·B J Whipp
Dec 1, 1993·The American Journal of Physiology·J T PottsP B Raven
Feb 1, 1996·Medicine and Science in Sports and Exercise·D S O'Leary
Sep 12, 1996·Journal of the Autonomic Nervous System·T MatsukawaT Mano
Feb 7, 1998·The Journal of Clinical Investigation·O E BroddeH R Zerkowski
Feb 17, 2001·American Journal of Physiology. Heart and Circulatory Physiology·P J FadelP B Raven
Apr 25, 2001·Circulation·M T La RovereUNKNOWN ATRAMI Investigators. Autonomic Tone and Reflexes After Myocardial Infarcton
Jun 19, 2001·American Journal of Physiology. Heart and Circulatory Physiology·K D MonahanH Tanaka
Jul 19, 2001·Annals of the New York Academy of Sciences·G ParatiG Mancia
Aug 4, 2001·Autonomic Neuroscience : Basic & Clinical·F Iellamo
Aug 18, 2001·Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology·M V Pitzalis
Apr 17, 2002·The Journal of Physiology·S OgohP B Raven
Aug 16, 2002·The Journal of Physiology·Rong ZhangBenjamin D Levine
Sep 17, 2003·Hypertension·Ruth D LipmanJ Andrew Taylor
Feb 10, 2004·Autonomic Neuroscience : Basic & Clinical·Daniela LuciniMassimo Pagani
Jul 10, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ken-Ichi IwasakiBenjamin D Levine
Jul 19, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Ferdinando IellamoMaurizio Volterrani
Oct 8, 2005·Experimental Physiology·Peter B RavenShigehiko Ogoh
Mar 2, 2006·Journal of Hypertension·Andrea DietrichJudith G M Rosmalen
Apr 29, 2006·Journal of Applied Physiology·Gianfranco ParatiPaolo Castiglioni
May 23, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Lachlan M McDowall, Roger A L Dampney
May 30, 2006·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Tulio Diaz, J Andrew Taylor

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Citations

Apr 5, 2011·American Journal of Physiology. Heart and Circulatory Physiology·Amy C ArnoldDebra I Diz
Jun 4, 2013·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Alessandra AdamiGuido Ferretti
Feb 10, 2010·The Journal of Physiology·James P FisherPaul J Fadel
Oct 7, 2009·The Journal of Physiology·James P FisherPaul J Fadel
Aug 9, 2015·Respiratory Physiology & Neurobiology·Nazzareno FagoniGuido Ferretti
Oct 18, 2011·Experimental Physiology·Paul J Fadel, Peter B Raven
Sep 14, 2014·European Journal of Applied Physiology·Andrea SivieriGuido Ferretti
Sep 9, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Toshinari AkimotoShigehiko Ogoh
Jan 20, 2018·American Journal of Physiology. Heart and Circulatory Physiology·André L TeixeiraLauro C Vianna
Apr 12, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Christopher E SchwartzJulian M Stewart
Apr 17, 2021·Frontiers in Physiology·Jin Woong KimHangsik Shin

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