PMID: 1203046Sep 1, 1975Paper

Spontaneous changes in blood pressure and aortal pulse wave velocity in normotensive subjects (results of a long term study in 183 men) author's transl)

Basic Research in Cardiology
W Schimmler, M Hooffacker

Abstract

The changes in the aortal pulse-wave velocity (PWV) occurring in connection with and dependent on spontaneous fluctuations of blood pressure has been recorded at intervals over the years in 183 normotensive men, who were aged from 17-74 at the beginning of the long term study. An essential condition was that the diastolic blood pressure should not exceed 95 mm Hg and the systolic 145 mm Hg. In order to eliminate the effect of age on the PWV between 2 measurements, and so to obtain a "pure" PWV-mean pressure relationship (c-p relationships), 7 cm/sec per year was subtracted from the c-value of the second measurement before the age of 55 and 9 cm/sec per year after that age. The differences quotient delta cp as a standard for the change of c with the mean pressure p was obtained from the difference between two c values (c1-c2) taken at different times, converted to a pressure change of 10 mm Hg, and divided by the difference of the mean pressure levels belonging to them (p1-p2). In applying the appropriate age correction to c2, the time factor had no statistically recognisable effect on delta cp. In 78% of the cases in our long term study, c rose and fell with p, in 22%, the changes of c were at variance with the changes of p. Ta...Continue Reading

References

Dec 1, 1969·The American Journal of Physiology·P B Dobrin, A A Rovick
Jan 1, 1958·Pflügers Archiv : European journal of physiology·H L THRONO H GAUER

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Citations

Apr 18, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Michinari FukudaTohru Izumi

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