Spontaneous formation of vesicles and chiral self-assemblies of sodium N-(4-dodecyloxybenzoyl)-L-valinate in water

Langmuir : the ACS Journal of Surfaces and Colloids
Ashok Mohanty, Joykrishna Dey

Abstract

A novel N-acylamino acid surfactant, sodium N-(4-dodecyloxybenzoyl)-L-valinate (SDLV), has been synthesized. The aggregation behavior of the surfactant in aqueous solution has been studied by surface tension, fluorescence probe, microscopy, and dynamic light scattering (DLS) techniques. The amphiphile has a very low critical aggregation concentration (cac). These studies have suggested formation of large bilayer structures in water. The mean apparent hydrodynamic radius, RH, of the self-assemblies in dilute aqueous solution obtained from DLS measurements confirmed formation of large aggregates. The FT-IR spectra of the amphiphile have indicated strong intermolecular amide hydrogen bonding in the self-assemblies in aqueous solution. The microenvironment of the fluorescence probes is highly nonpolar and viscous in nature. The circular dichroism (CD) spectra of SDLV were recorded in water and in a 1:1 water-methanol mixture. The CD spectra have indicated the presence of chiral aggregates in aqueous solution above the cac. The microstructure of the aggregates has been studied by use of optical and transmission electron microscopy. Both types of micrographs have shown the presence of a variety of morphologies including giant spheric...Continue Reading

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Citations

Jul 17, 2010·Journal of Colloid and Interface Science·Saurabh Shrivastava, Joykrishna Dey
Jan 26, 2010·Journal of Colloid and Interface Science·Trilochan PatraJoykrishna Dey
Apr 8, 2015·Advances in Colloid and Interface Science·Romain Bordes, Krister Holmberg
Mar 13, 2012·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Denis V AnokhinDimitri A Ivanov
Dec 10, 2009·Chemistry : a European Journal·Ignacio AlfonsoSantiago V Luis
May 10, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Gerhard BilekErnst Kenndler
May 3, 2005·Journal of Chromatography. a·Ashok Mohanty, Joykrishna Dey
May 13, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Wenrong ZhaoJingcheng Hao
Oct 18, 2011·International Journal of Pharmaceutics·Pranabesh Dutta, Joykrishna Dey
Mar 18, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Arjun Ghosh, Joykrishna Dey
Apr 13, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Trilochan PatraJoykrishna Dey
Mar 29, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·S Shankara Gayathri, Archita Patnaik
Jun 8, 2007·The Journal of Physical Chemistry. B·Ashok MohantyJoykrishna Dey
Sep 15, 2006·The Journal of Physical Chemistry. B·Rodrigo O BritoOlle Söderman

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