Spontaneous regression of optic pathways gliomas in three patients with neurofibromatosis type I and critical review of the literature.

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Manolo PiccirilliAntonino Raco

Abstract

The authors report their experience about three children (two girls, one boy; average age 1.6 years) with a spontaneous regression of optic gliomas. All of them had a previous diagnosis of neurofibromatosis type 1 (NF 1). None of them underwent surgery or biopsy nor received chemotherapy or radiotherapy. The complete regression was documented by MRI scans performed during a mean follow-up of 6.3 years. Moreover, the authors analyze the features of the 16 cases previously reported in English literature of spontaneously regressed optic gliomas with an overview of the different therapeutic strategies. The knowledge that this kind of tumor, particularly in young patients, may regress is important in the decision of the best therapeutic approach.

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Citations

Mar 29, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Emre CecenNur Olgun
Oct 12, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Markus HuppMonika Warmuth-Metz
Jan 23, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Seong Rok HanChae Heuck Lee
Jun 19, 2014·BMC Ophthalmology·Maria Giuseppina CefaloAngela Mastronuzzi
Mar 1, 2013·CNS Oncology·Iris FriedEric Bouffet
Feb 26, 2014·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Tafadzwa MandiwanzaJohn Caird
Mar 19, 2013·World Neurosurgery·Concezio Di RoccoGianpiero Tamburrini
Mar 22, 2012·Current Problems in Pediatric and Adolescent Health Care·Adam J Fleming, Susan N Chi
May 28, 2008·Pediatric Neurosurgery·Warren Matthew RozenPatrick Anthony Lo
Jan 22, 2009·Current Opinion in Neurology·Helmut Wilhelm
Aug 23, 2011·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Robert A AveryGrant T Liu
Apr 16, 2020·The Journal of Clinical Endocrinology and Metabolism·Claudia SantoroAnna Grandone
Feb 6, 2015·Expert Review of Anticancer Therapy·Nicole M Brossier, David H Gutmann
Aug 15, 2017·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Peter M K de BlankRobert A Avery
Jun 12, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ben ShoftyShlomi Constantini
Mar 31, 2010·Journal of Neuro-oncology·Pablo Hernáiz DrieverAstrid K Gnekow
Jun 17, 2021·Neuro-oncology·Till MildeDavid H Gutmann
Oct 31, 2017·Survey of Ophthalmology·Michael KinoriJanice Lasky Zeid

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