Spontaneous Selective Preconcentration Leveraged by Ion Exchange and Imbibition through Nanoporous Medium

Scientific Reports
Dokeun LeeSung Jae Kim

Abstract

Manipulating mechanism of particle's motion has been extensively studied for the sample preparation in microfluidic applications including diagnostics, food industries, biological analyses and environmental monitoring. However, most of conventional methods need additional external forces such as electric field or pressure and complicated channel designs, which demand highly complex fabrication processes and operation strategies. In addition, these methods have inherent limitations of dilution or mixing during separation or preconcentration step, respectively, so that a number of studies have reported an efficient selective preconcentration process, i.e. conducting the separation and preconcentration simultaneously. In this work, a power-free spontaneous selective preconcentration method was suggested based on leveraging convective flow over diffusiophoresis near the water-absorbing nanoporous ion exchange medium, which was verified both by simulation and experiment. Especially, the velocity of the convective flow by an imbibition deviated from the original tendency of t-1/2 due to non-uniformly patterned nanoporous medium that has multiple cross-sectional areas. As a result, the direction of particle's motion was controlled at ...Continue Reading

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Citations

Dec 13, 2019·Lab on a Chip·Jihye ChoiSung Jae Kim
Sep 11, 2020·Lab on a Chip·Myungjin SeoSung Jae Kim
Dec 21, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Trevor J ShimokusuSangwoo Shin
Sep 11, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Patrick L Fosso TeneJürgen Rühe

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