DOI: 10.1101/518712Jan 14, 2019Paper

Spontaneously emerging cortical representations of visual objects and features in human visual cortex

BioRxiv : the Preprint Server for Biology
DoHyun KimGordon L Shulman


The function of spontaneous brain activity is unknown. Here we test the novel hypothesis that patterns of spontaneous activity reflect not only synaptic homeostasis or synchronization of neuronal populations, but code representational patterns evoked by stimuli and tasks. We compared in visual cortex the spatial patterns of spontaneous activity to the patterns evoked by ecological visual stimuli (faces, bodies, scenes) and low-level visual features (e.g. phase-scrambled faces). We identified regions that preferred particular stimulus categories during localizer scans, measured multivariate spatial patterns for each category during task scans, and then spatially correlated these stimulus-evoked patterns to the pattern measured in each frame of resting-state scans. The mean correlation coefficient was essentially zero for all regions/stimulus categories, indicating that resting activity patterns were not biased toward particular stimulus categories. However, the spread of correlation coefficients, i.e. both positive and negative, was significantly greater for a stimulus category over the ROIs preferring that category (e.g. the body category in body-preferring ROIs). Therefore, the putative representational content of spontaneous ...Continue Reading

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Cerebral Cortex
Neoplasms, Multiple Primary
Visual Cortex
Brain Activity
Population Group

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