Sporadic bilateral adrenal medullary hyperplasia: apparent false positive MIBG scan and expected MRI findings

European Journal of Radiology
B C YungJ C Chan


Adrenal medullary hyperplasia is a rare cause of clinical symptoms and biochemical findings identical to pheochromocytoma occurring mostly in multiple endocrine neoplasia patients. The scenario of positive MIBG scan, but no focal lesion found on CT and MRI led to diagnostic and management difficulties. Like pheochromocytoma, surgical excision can lead to clinical and biochemical recovery. We report this unusual case of sporadic bilateral adrenal medullary hyperplasia, with hypertension and biochemical abnormalities alleviated after surgical adrenalectomy. Based on T2 values reported in literature, high signal focal lesions may not appear on T2-weighted MRI images until development of frank pheochromocytoma. MIBG scan remains the most sensitive imaging modality for this condition.


Apr 1, 1975·Journal of Clinical Pathology·J W Visser, R Axt
Jun 1, 1988·Clinical Nuclear Medicine·J J YobbagyT Polley
Jan 13, 1998·Clinical Endocrinology·G QuptyR Luboshitzky
Jan 27, 1998·Clinical Nuclear Medicine·Y YamamotoM Tanabe

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