Sporadic cutaneous lymphosarcoma of T-cell origin with involvement of lymph nodes and internal organs in a Holstein cow

Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
M FreickS Schöniger

Abstract

Sporadic lymphosarcomas in adult cattle are rare entities with an unknown etiology. This case report describes the course of the disease in a 3.5-year-old cow of the breed German Holstein, which was presented to the veterinarian due to multifocal nodular skin lesions. Several superficial lymph nodes (Lymphonodi mandibulares, parotidei and mammariae) were enlarged, had a tight-elastic consistency and were freely movable. The histopathological and immunohistochemical examination of skin biopsies showed the presence of multifocal cutaneous T-cell lymphosarcomas consistent with a skin leukosis. Bovine leukemia virus infection was excluded by serological investigation of a milk sample and virological examination of a tissue sample, respectively. Seven weeks after the first clinical examination, the cow deteriorated rapidly and was euthanized. A post mortem examination revealed the presence of neoplastic cells within lymph nodes (all superficial lymph nodes of the carcass and Lymphonodi pulmonales), kidney and lungs as well as a liver rupture. Additionally, an overview of the case reports of sporadic bovine cutaneous lymphosarcomas published during the previous 15 years will be provided. The legal background for a further utilization...Continue Reading

References

May 1, 1978·Veterinary Pathology·A C Johnstone, B W Manktelow
Mar 1, 1989·Veterinary Pathology·K OkadaH Koyama
Nov 1, 1987·Veterinary Pathology·R D ZwahlenA Schneider
Jul 5, 2001·Journal of Comparative Pathology·K KadotaT Shibahara
Jun 20, 2006·Veterinary Clinical Pathology·Martina Klinkon, Manica Cerne
Jul 5, 2007·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Shinji YamamotoKoichi Kadota
May 15, 2008·Veterinary Dermatology·Kiran S PalyadaMelissa Czajkowski
Nov 5, 2010·The Journal of Veterinary Medical Science·Mitsuru ItoKoichi Kadota
Apr 1, 2011·Schweizer Archiv für Tierheilkunde·U BraunT Sydler
Apr 18, 2015·BMC Veterinary Research·Nicole S GollnickMartin C Langenmayer

❮ Previous
Next ❯

Citations

Jun 18, 2011·BMC Veterinary Research·Hannah LenzkoLisa D Sprague
Sep 19, 2017·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Zoltan S GyimesiRita McManamon
Sep 22, 2017·Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·Julia HankelMichael Fehr

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.