Spot check analysis of gas exchange: invasive versus noninvasive methods

Respiration; International Review of Thoracic Diseases
Emelie EkkernkampJan H Storre

Abstract

Correct measurement of PO₂ and PCO₂ is essential to establish appropriate therapy such as long-term oxygen therapy (LTOT) in patients suffering from respiratory failure. We aimed to compare common invasive and noninvasive methods for assessing blood gas components for spot check analysis. Arterial (PaO₂, PaCO₂) and capillary blood gas (PCBGO2, PCBGCO2) measurements were taken consecutively in a randomized order and were compared with noninvasive measurements obtained from the transcutaneous monitoring of PO₂ and PCO₂ (PtcOv, PtcCO₂, sensor-temperature 44°C). Capillary samples were taken from both arterialized earlobes, where samples of right earlobes were defined as a reference value. Pain assessment of all measurements was evaluated by each subject using the 100-mm visual analogue scale. 83 patients and 17 healthy subjects were included. The mean difference between PaO₂ and PtcO₂ was 11.9 ± 15.0 mm Hg, with lower limits of agreement (LLA) of -17.4 mm Hg (95% confidence interval (CI) -22.5 to -12.3 mm Hg), and upper limits of agreement (ULA) of 41.1 mm Hg (95% CI 36.0-46.2 mm Hg). The comparison of PaO₂ with PCBGO2 showed a mean difference of 5.6 ± 7.2 mm Hg (LLA -11.0; ULA 19.6 mm Hg). The mean difference between PaCO₂ and Ptc...Continue Reading

Citations

Apr 7, 2016·Medizinische Klinik, Intensivmedizin und Notfallmedizin·F S MagnetJ H Storre
Apr 30, 2017·Expert Review of Respiratory Medicine·F S MagnetW Windisch
Oct 11, 2020·Scientific Reports·Björn BalcerekMichael Fähling
Dec 9, 2020·Pneumologie·P HaidlUNKNOWN Deutsche Sauerstoff- und BeatmungsLiga LOT e. V.
Jan 1, 2021·Pediatric Pulmonology·Manuela DicembrinoVivian Leske
Sep 3, 2021·Pneumologie·Jens GottliebThomas Fühner
Oct 16, 2021·Medizinische Klinik, Intensivmedizin und Notfallmedizin·Jens GottliebThomas Fühner
Dec 11, 2020·Respiration; International Review of Thoracic Diseases·Jean-Paul JanssensUNKNOWN on behalf of the Special Interest Group on Ventilation and Oxygen Therapy of the Swiss Society of Pneumology

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