Spotted leaf11, a negative regulator of plant cell death and defense, encodes a U-box/armadillo repeat protein endowed with E3 ubiquitin ligase activity

The Plant Cell
Li-Rong ZengGuo-Liang Wang

Abstract

The rice (Oryza sativa) spotted leaf11 (spl11) mutant was identified from an ethyl methanesulfonate-mutagenized indica cultivar IR68 population and was previously shown to display a spontaneous cell death phenotype and enhanced resistance to rice fungal and bacterial pathogens. Here, we have isolated Spl11 via a map-based cloning strategy. The isolation of the Spl11 gene was facilitated by the identification of three additional spl11 alleles from an IR64 mutant collection. The predicted SPL11 protein contains both a U-box domain and an armadillo (ARM) repeat domain, which were demonstrated in yeast and mammalian systems to be involved in ubiquitination and protein-protein interactions, respectively. Amino acid sequence comparison indicated that the similarity between SPL11 and other plant U-box-ARM proteins is mostly restricted to the U-box and ARM repeat regions. A single base substitution was detected in spl11, which results in a premature stop codon in the SPL11 protein. Expression analysis indicated that Spl11 is induced in both incompatible and compatible rice-blast interactions. In vitro ubiquitination assay indicated that the SPL11 protein possesses E3 ubiquitin ligase activity that is dependent on an intact U-box domain...Continue Reading

References

Apr 25, 1997·Journal of Molecular Biology·C Burge, S Karlin
Feb 13, 1999·Cell·D L Vaux, S J Korsmeyer
Apr 17, 1999·The Plant Journal : for Cell and Molecular Biology·A TakahashiK Shimamoto
Mar 8, 2000·Current Biology : CB·L Aravind, E V Koonin
Jun 8, 2001·The Plant Journal : for Cell and Molecular Biology·C KirschK Hahlbrock
Jul 4, 2001·The Journal of Biological Chemistry·S HatakeyamaK I Nakayama
Aug 2, 2001·Proceedings of the National Academy of Sciences of the United States of America·P KachrooD F Klessig
Aug 10, 2001·Trends in Plant Science·C AzevedoK Shirasu
Sep 15, 2001·The Journal of Biological Chemistry·J JiangC Patterson
Dec 26, 2001·Bioinformatics·S KumarM Nei
Feb 16, 2002·Science·Cristina AzevedoPaul Schulze-Lefert
May 29, 2002·Proceedings of the National Academy of Sciences of the United States of America·Utako YamanouchiKyoji Yamada
Oct 24, 2002·Current Opinion in Plant Biology·Hideo Kuriyama, Hiroo Fukuda
Mar 11, 2003·Nature Structural Biology·Melanie D OhiKathleen L Gould
May 20, 2003·Immunological Reviews·Justine C Lee, Marcus E Peter
Jun 24, 2003·Trends in Plant Science·Séverine LorrainDominique Roby
Jul 23, 2003·Current Opinion in Plant Biology·Alessandra DevotoKen Shirasu
Aug 2, 2003·Biochemical and Biophysical Research Communications·Kou MiyazakiAkira Nakagawara
Aug 29, 2003·The Plant Journal : for Cell and Molecular Biology·Yan WuFumiaki Katagiri
Nov 25, 2003·Nature Reviews. Genetics·James A SullivanXing Wang Deng
Jun 1, 1997·Annual Review of Plant Physiology and Plant Molecular Biology·Jean T. Greenberg
Aug 1, 1991·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·S Weining, P Langridge

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Citations

Dec 14, 2007·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Chang-Jiang ZhaoGuo-Dong Lu
Jul 22, 2009·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Qin YaoJizeng Jia
Dec 7, 2010·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Raman BabuShinji Kawasaki
Jun 1, 2012·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Haiying GuanJinsheng Lai
Mar 22, 2008·Molecular Genetics and Genomics : MGG·Changjian WuHei Leung
Apr 19, 2011·Plant Molecular Biology·Ting GaoQi Xie
Feb 13, 2013·Plant Molecular Biology·Chung-Yi LinHao-Jen Huang
May 25, 2006·Nature Methods·Hideo MatsumuraRyohei Terauchi
Aug 29, 2006·Nature Reviews. Molecular Cell Biology·Robert B AbramovitchGregory B Martin
Mar 12, 2009·Journal of Experimental Botany·Adam CraigAri Sadanandom
Nov 10, 2007·Molecular Plant-microbe Interactions : MPMI·Saeed IrianMarilyn J Roossinck
May 13, 2005·Plant Physiology·Chatchawan JantasuriyaratGuo-Liang Wang
Jun 13, 2012·Plant Physiology·Daniel MarinoSusana Rivas
Nov 23, 2006·The Plant Cell·Wubei DongPatrick Schweizer
Aug 12, 2005·Genome Génome / Conseil National De Recherches Canada·Fuzhen LiZongxiu Sun
Mar 20, 2008·PloS One·Norman WarthmannPhilippe Hervé

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