Spray-dried plasma improves growth performance and reduces inflammatory status of weaned pigs challenged with enterotoxigenic Escherichia coli K88

Journal of Animal Science
P BosiE Mengheri

Abstract

We investigated whether spray-dried plasma (SDP) improved growth and health of piglets challenged with enterotoxigenic Escherichia coli K88 (ETEC). Forty-eight pigs weaned at 21 d (BW = 4.88 +/- 0.43 kg) received one of four diets containing 6% SDP or fish proteins (as-fed basis) either nonmedicated (SDP-NM and FP-NM diets) or medicated with 0 or 250 mg/kg of colistine + 500 mg/kg of amoxycycline (SDP-M and FP-M diets), for 15 d. On d 4, pigs were orally challenged with ETEC. On d 15, eight pigs per dietary group were killed, blood and saliva were collected for analysis of K88 fimbriae-specific immunoglobulin (Ig)-A, and jejunum was removed for villi preparation, histological analysis, and cytokine expression. The presence or absence of K88 receptors (K88+ and K88- pigs respectively) was determined by villous adhesion assay. Effects of protein source on ADG (P = 0.04) and ADFI (P < 0.01), as well of medication on ADFI (P < 0.02), of all pigs were observed. In sacrified pigs, there was an effect of protein source on ADG (P = 0.03) and ADFI (P < 0.001), as well an interaction between medication and presence of K88 receptor (P = 0.02) for feed:gain ratio. Plasma K88 specific IgA were low in all K88 pigs and higher in K88+ pigs fed...Continue Reading

Associated Clinical Trials

Nov 20, 2015·Rachel Herdes

References

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Citations

Dec 1, 2009·Animal : an International Journal of Animal Bioscience·J P LallèsD Torrallardona
Apr 18, 2014·Animal : an International Journal of Animal Bioscience·V BontempoA Agazzi
Feb 9, 2019·Journal of Animal Physiology and Animal Nutrition·Diana LuisePaolo Trevisi
Jun 19, 2019·Journal of Animal Science and Biotechnology·Diana LuisePaolo Trevisi
Jul 27, 2020·Translational Animal Science·Joice V San AndresThomas E Burkey
May 1, 2007·The Proceedings of the Nutrition Society·Jean-Paul LallèsChris R Stokes
Nov 30, 2007·Journal of Food Protection·Shivani Ojha, Magdalena Kostrzynska
Oct 1, 2010·Animal : an International Journal of Animal Bioscience·P BalanP J Moughan
Sep 13, 2011·The British Journal of Nutrition·Mònica MaijóAnna Pérez-Bosque
Aug 30, 2020·Journal of Animal Physiology and Animal Nutrition·Prabhu BalanPaul J Moughan
Oct 7, 2004·The Journal of Nutrition·Anna Pérez-BosqueMiquel Moretó
Jun 26, 2010·The Proceedings of the Nutrition Society·Anna Pérez-Bosque, Miquel Moretó
Sep 6, 2007·Journal of Animal Science·J D CrenshawM E Wilson
Dec 1, 2009·Animal : an International Journal of Animal Bioscience·M GalloisI P Oswald

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