Abstract
The USA300 clone is a highly-virulent community-acquired methicillin-resistant Staphylococcus aureus, which has been predominant in the United States. In a previous study, we isolated the USA300 clone from an 11-month-old Japanese girl, who lived in Saitama (Japan), and suffered from cellulitis and sepsis, and subsequently osteomyelitis, in 2008. In this study, we searched for the source of such USA300 infection in three related families (the patient's grandfather and grandmother, having a USA300-infected daughter [F2D], and a mother [F3M] who was a sister of F2D's mother). In January, 2008, F3M and her family members visited Hawaii and were treated in a hospital for gastroenteritis (with diarrhea) with an intravenous drip for F3M. After their return to Japan in January, F3M suffered from unusually frequent (more than 10 times) skin soft-tissue infections (SSTIs) until successful chemotherapy in July in Saitama. In the same summer season, SSTI was observed in 7 of 11 family members (63.6%). This dense spread of SSTI was followed by cellulitis and sepsis (USA300-isolated case) in October and subsequent osteomyelitis in December in F2D. After successful chemotherapy for the patient (F2D), no new SSTI cases were observed among the...Continue Reading
References
Sep 12, 2003·Emerging Infectious Diseases·Francois VandeneschJerome Etienne
Aug 18, 2006·The New England Journal of Medicine·Gregory J MoranUNKNOWN EMERGEncy ID Net Study Group
Jan 20, 2007·Science·Maria Labandeira-ReyM Gabriela Bowden
Apr 3, 2008·The Pediatric Infectious Disease Journal·Karen C HayaniKristina G Hulten
Dec 18, 2008·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Yasuhiro ShibuyaTatsuo Yamamoto
Jul 18, 2009·The Journal of Antimicrobial Chemotherapy·Fred C Tenover, Richard V Goering
Mar 23, 2010·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Wataru HiguchiTatsuo Yamamoto
Mar 26, 2010·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Tatsuo YamamotoDa Shi
Citations
Oct 23, 2012·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Mitsuyo KawaguchiyaNobumichi Kobayashi
Jan 16, 2013·Antimicrobial Agents and Chemotherapy·Tomomi TakanoTatsuo Yamamoto
Mar 1, 2012·Therapeutics and Clinical Risk Management·Mao HagiharaHiroshige Mikamo
Apr 14, 2015·Trends in Microbiology·Justin KnoxFranklin D Lowy
Feb 22, 2012·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Yasuhisa IwaoTatsuo Yamamoto
Dec 14, 2011·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Tatsuo YamamotoAkihito Nishiyama
Jan 10, 2012·International Journal of Antimicrobial Agents·Robert SkovFranklin D Lowy
Jun 5, 2014·Journal of Travel Medicine·Yvonne P ZhouLi-Yang Hsu
Aug 16, 2013·Journal of Medical Microbiology·Mitsuyo KawaguchiyaNobumichi Kobayashi
Mar 3, 2015·Journal of Dairy Science·Sophia JohlerRoger Stephan
Nov 15, 2012·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Tadashi MaedaKazuhiro Tateda
Oct 20, 2018·Internal Medicine·Hiroki KitagawaMotoyuki Sugai
Sep 29, 2019·International Journal of STD & AIDS·Yoshihiko OgawaKeiichi Mikasa
Apr 17, 2020·Internal Medicine·Hirofumi YamagishiTakeshi Inazawa
Oct 19, 2017·Journal of the Pediatric Infectious Diseases Society·Eduardo A LindsayLawson A Copley
Oct 16, 2020·The Journal of Infectious Diseases·Kazuhiko IkeuchiHiroshi Yotsuyanagi
May 10, 2021·Journal of Global Antimicrobial Resistance·Fernanda Pimentel de AraujoAnnalisa Pantosti