Spread of the community-acquired methicillin-resistant Staphylococcus aureus USA300 clone among family members in Japan

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Shizuka YabeTatsuo Yamamoto

Abstract

The USA300 clone is a highly-virulent community-acquired methicillin-resistant Staphylococcus aureus, which has been predominant in the United States. In a previous study, we isolated the USA300 clone from an 11-month-old Japanese girl, who lived in Saitama (Japan), and suffered from cellulitis and sepsis, and subsequently osteomyelitis, in 2008. In this study, we searched for the source of such USA300 infection in three related families (the patient's grandfather and grandmother, having a USA300-infected daughter [F2D], and a mother [F3M] who was a sister of F2D's mother). In January, 2008, F3M and her family members visited Hawaii and were treated in a hospital for gastroenteritis (with diarrhea) with an intravenous drip for F3M. After their return to Japan in January, F3M suffered from unusually frequent (more than 10 times) skin soft-tissue infections (SSTIs) until successful chemotherapy in July in Saitama. In the same summer season, SSTI was observed in 7 of 11 family members (63.6%). This dense spread of SSTI was followed by cellulitis and sepsis (USA300-isolated case) in October and subsequent osteomyelitis in December in F2D. After successful chemotherapy for the patient (F2D), no new SSTI cases were observed among the...Continue Reading

References

Aug 18, 2006·The New England Journal of Medicine·Gregory J MoranUNKNOWN EMERGEncy ID Net Study Group
Jan 20, 2007·Science·Maria Labandeira-ReyM Gabriela Bowden
Apr 3, 2008·The Pediatric Infectious Disease Journal·Karen C HayaniKristina G Hulten
Dec 18, 2008·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Yasuhiro ShibuyaTatsuo Yamamoto
Jul 18, 2009·The Journal of Antimicrobial Chemotherapy·Fred C Tenover, Richard V Goering
Mar 23, 2010·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Wataru HiguchiTatsuo Yamamoto
Mar 26, 2010·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Tatsuo YamamotoDa Shi

❮ Previous
Next ❯

Citations

Oct 23, 2012·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Mitsuyo KawaguchiyaNobumichi Kobayashi
Mar 1, 2012·Therapeutics and Clinical Risk Management·Mao HagiharaHiroshige Mikamo
Apr 14, 2015·Trends in Microbiology·Justin KnoxFranklin D Lowy
Feb 22, 2012·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Yasuhisa IwaoTatsuo Yamamoto
Dec 14, 2011·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Tatsuo YamamotoAkihito Nishiyama
Jan 10, 2012·International Journal of Antimicrobial Agents·Robert SkovFranklin D Lowy
Jun 5, 2014·Journal of Travel Medicine·Yvonne P ZhouLi-Yang Hsu
Oct 19, 2017·Journal of the Pediatric Infectious Diseases Society·Eduardo A LindsayLawson A Copley
Oct 16, 2020·The Journal of Infectious Diseases·Kazuhiko IkeuchiHiroshi Yotsuyanagi
May 10, 2021·Journal of Global Antimicrobial Resistance·Fernanda Pimentel de AraujoAnnalisa Pantosti

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Cellulitis

Cellulitis (erysipelas) is a recurring and debilitating bacterial infection of the skin and underlying tissue. Discover the latest research on cellulitis here.

Related Papers

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Wataru HiguchiTatsuo Yamamoto
Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Tatsuo YamamotoAkihito Nishiyama
Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Yasuhisa IwaoTatsuo Yamamoto
© 2021 Meta ULC. All rights reserved