Squamous cell carcinoma of the penis: multivariate analysis of prognostic factors and natural history in monocentric study with a conservative policy

Annals of Oncology : Official Journal of the European Society for Medical Oncology
J C SoriaC Théodore

Abstract

Penile carcinoma is uncommon in Western countries. Here we report on a large series of patients with squamous cell carcinoma (SCC) of the penis, describing prognostic factors, survival and therapeutic results. From 1973 to 1993, 102 patients with invasive SCC of the penis were treated at the Institut Gustave-Roussy. Precancerous lesions and conditions associated with penis cancer were analyzed retrospectively. Survival curves were estimated by the Kaplan-Meier method, and groups were compared for outcome by the log rank test for univariate comparisons and by Cox's proportional hazards model for multivariate analysis. The median age at onset was 58 years. Sixty-nine patients presented with Jackson's stage I disease, 17 with stage II and 15 with stage III. The interval between the manifestation of symptoms and the diagnosis was more than a year in 13.7% of cases. Precancerous lesions were found in 17 (16.6%) patients, and a history of phimosis was noted in 25 (24.5%). In situ and invasive carcinoma were observed together in 17 (16.6%) cases and dysplasia was associated with invasive carcinoma in eight (7.8%) further cases. Conservative treatment was administered whenever feasible. Interstitial brachytherapy was performed alone or...Continue Reading

References

Nov 1, 1979·Cancer·S GrahamD West
Oct 1, 1977·Cancer·Z WajsmanG P Murphy
Oct 11, 1976·The Journal of Urology·B H BakerR J Leduc
May 1, 1991·British Journal of Urology·A G MaicheM Karkinen
Sep 1, 1986·CA: a Cancer Journal for Clinicians·L Persky, J deKernion
Nov 21, 1987·British Medical Journal·D HellbergS Nilsson
Apr 1, 1985·Cancer·E E FraleyP H Lange
Feb 1, 1972·The Journal of Urology·D G SkinnerS B Kelley
Sep 1, 1973·The Journal of Urology·F C DerrickW J Yarbrough
Sep 1, 1972·The Journal of Urology·G J HardnerR H Moore
Aug 1, 1970·The Journal of Urology·K A HanashE G Harrison
Jan 1, 1966·The British Journal of Surgery·S M Jackson
Oct 1, 1984·International Journal of Radiation Oncology, Biology, Physics·J J MazeronB Pierquin
May 15, 1982·Cancer·A S NarayanaD A Culp
Aug 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R RozanA Goupil
Mar 1, 1995·British Journal of Urology·K Harish, R Ravi
Nov 1, 1994·The Journal of Urology·A L SeixasJ R de Moraes
May 1, 1994·British Journal of Urology·S OpjordsmoenS D Fossa
May 1, 1994·The Journal of Urology·W S McDougal
Dec 2, 1995·BMJ : British Medical Journal·M FrischM Melbye
Jun 1, 1963·Cancer·M RIVEROS, R F LEBRON
Apr 1, 1980·Cancer·Claude E Merrin

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Citations

Sep 1, 2007·Scandinavian Journal of Urology and Nephrology·Beata PerssonUNKNOWN Steering Committee of the National Penile Cancer Register in Sweden
Jul 19, 2008·World Journal of Urology·Juanita CrookLaval Grimard
Aug 5, 2011·International Urology and Nephrology·Jonathan E HeinlenDaniel Joseph Culkin
Nov 2, 2015·The Kaohsiung Journal of Medical Sciences·Jiun-Hung GengChao-Yuan Huang
Jun 3, 2004·International Journal of Surgical Pathology·Elsa F VelazquezAntonio L Cubilla
Feb 14, 2004·The Australasian Journal of Dermatology·John P Arlette, Martin J Trotter
Oct 21, 2004·International Journal of Surgical Pathology·Antonio L CubillaRobert H Young
May 6, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Bin K KroonSimon Horenblas
Jan 11, 2013·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Paulo OrnellasFulvio Magni
Nov 5, 2016·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Giuliano Amorim AitaThais Safranov Giuliangelis
Oct 13, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·R E EmersonL Cheng
Jan 17, 2002·The Journal of Urology·Juanita CrookTony Panzarella
Dec 22, 2004·BJU International·Alastair W S RitchieUNKNOWN BAUS Section of Oncology
Jan 21, 2006·Journal of Surgical Oncology·Durgatosh PandeyR Ravi Kannan
Sep 12, 2007·Der Urologe. Ausg. A·A Heidenreich, G Jakse
Jul 19, 2008·The Journal of Urology·Joost A P LeijteSimon Horenblas
Feb 19, 2014·Virchows Archiv : an International Journal of Pathology·Ch KakiesCh Protzel
Aug 24, 2018·Ciência & saúde coletiva·Marco Antônio Comper de SouzaMaria Helena Costa Amorim
Sep 4, 2008·World Journal of Urology·Antonio L Cubilla
May 24, 2011·Advances in Urology·Maria Carmen MirNathan Lawrentschuk
Aug 12, 2008·World Journal of Urology·Joost A P Leijte, Simon Horenblas
Feb 5, 2021·Clinical and Translational Radiation Oncology·Nicolas MartzJean-Michel Hannoun-Levi
Feb 13, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A ZouhairM Ozsahin
Apr 5, 2000·Clinical Oncology : a Journal of the Royal College of Radiologists·A E KiltieD V Ash
May 9, 2002·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C ThéodoreP Wibault
Dec 25, 2003·Urologic Oncology·Samira SyedGeoffrey R Weiss
Jan 8, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G SonpavdeG Di Lorenzo
Dec 19, 2003·The Urologic Clinics of North America·Ricardo F Sánchez-Ortiz, Curtis A Pettaway
Sep 5, 2006·International Journal of Radiation Oncology, Biology, Physics·Mahmut OzsahinAbderrahim Zouhair
Jun 20, 2014·Radiation Oncology·Yohann RouscoffJean-Michel Hannoun-Levi
Apr 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Renaud de CrevoisierChristine Haie-Meder
Nov 3, 2009·Urologic Oncology·Roberto SalvioniNicola Nicolai
Aug 19, 2010·Urology·Chris F HeynsAntonio C L Pompeo
Aug 19, 2010·Urology·Eduardo SolsonaNick A Watkin
Aug 19, 2010·Urology·Chris F HeynsHendrik van Poppel

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