PMID: 2106343Feb 26, 1990Paper

Squid proteoglycans: isolation and characterization of three populations from cranial cartilage

Biochimica Et Biophysica Acta
D H Vynios, C P Tsiganos

Abstract

Squid cranial cartilage is poor in proteoglycans. They were extracted by 2% SDS and purified by isopycnic centrifugation in the presence of detergent. According to their buoyant density and hydrodynamic size they were fractionated into three structurally different populations of Mr 1.3.10(6), 0.6.10(6) and 1.0.10(6). The proteoglycans of each population differ in the number of oversulphated chondroitin sulphate chains, ranging from two to five, in the number and size of uronic acid and sulphate containing oligosaccharides and in the size of their core protein. The majority, if not all, of the oligosaccharides are linked to the protein via an O-glycosidic bond involving galactosamine and most likely xylose. The chondroitin sulphate chains are segregated on a small peptide segment of the molecule which also contains a large proportion of the oligosaccharides. The proteoglycans have no tendency to interact with hyaluronate.

References

Dec 1, 1973·Developmental Biology·T F LinsenmayerR L Trelstad
Jul 1, 1996·The British Journal of Surgery·K VartyN J London
Sep 19, 2002·Analytical Chemistry·Rebecca J WhelanRichard N Zare
Oct 1, 1962·Analytical Biochemistry·T BITTER, H M MUIR

❮ Previous
Next ❯

Citations

May 15, 1993·Experientia·N S Fedarko
Jan 1, 1991·The International Journal of Biochemistry·N K KaramanosC A Antonopoulos
Jan 18, 2003·The International Journal of Biochemistry & Cell Biology·Achilleas D TheocharisDimitrios A Theocharis
Aug 28, 1990·European Journal of Biochemistry·K K KaramanosC P Tsiganos
Dec 1, 1992·Matrix : Collagen and Related Research·D H VyniosC P Tsiganos
Sep 24, 2004·Biomedical Chromatography : BMC·I E TriantaphyllidouD H Vynios
Jun 10, 2011·Communicative & Integrative Biology·Shuhei YamadaSuat Ozbek
Jun 24, 2008·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·J von ByernW Klepal
Oct 19, 2017·Critical Reviews in Food Science and Nutrition·Ling Chong WangHao Wu
Apr 12, 2002·The Journal of Biological Chemistry·Toshio NinomiyaKoji Kimata
Oct 16, 1999·International Journal of Biological Macromolecules·A D TheocharisT Tsegenidis
Oct 3, 1993·Biochimica Et Biophysica Acta·P PaschalakisP G Koutsoukos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.