Get paper from

journal cover

SSA-ME Detection of cancer driver genes using mutual exclusivity by small subnetwork analysis

Scientific Reports

Nov 3, 2016

Sergio Pulido-TamayoKathleen Marchal

Get paper from

Abstract

Because of its clonal evolution a tumor rarely contains multiple genomic alterations in the same pathway as disrupting the pathway by one gene often is sufficient to confer the complete fitness advantage. As a result, many cancer driver genes display mutual exclusivity across tumors. Ho...read more

7
24
Paper Details
References
    • References35
    • Citations2
    • References35
    • Citations2
  • SSA-ME Detection of cancer driver genes using mutual exclusivity by small subnetwork analysis

    Scientific Reports

    Nov 3, 2016

    Sergio Pulido-TamayoKathleen Marchal

    PMID: 27808240

    DOI: 10.1038/srep36257

    Abstract

    Because of its clonal evolution a tumor rarely contains multiple genomic alterations in the same pathway as disrupting the pathway by one gene often is sufficient to confer the complete fitness advantage. As a result, many cancer driver genes display mutual exclusivity across tumors. Ho...read more

    7
    24

    Related Papers

    Paper Details
    References
    • References35
    • Citations2
    • References35
    • Citations2
  • Get paper from

    © 2019 Meta ULC. All rights reserved.

    Hi! We use cookies on this site for analytics purposes. Visit our cookie policy to learn more. By continuing to use our services or closing this banner, you consent to our use of cookies.

    /papers/ssa-me-detection-of-cancer-driver-genes-using/27808240