PMID: 16526272Mar 11, 2006Paper

St. George's respiratory questionnaire (SGRQ) in sarcoidosis patients

Medicinski pregled
Vladimir ZugićBranislav Gvozdenović

Abstract

Sarcoidosis is a chronic multisystem disorder which has a great impact on health-related quality of life (HRQL). Patients with sarcoidosis very often present with bronchial obstruction. The purpose of this study was to assess the impact of respiratory disorder on general HRQL using St. George's respiratory questionnaire (SGRQ). We examined 129 patients with histologically proven sarcoidosis. All patients underwent clinical examination, chest X-ray and spirometry, and in all skin prick tests and sera ACE and IgE were determined. Afterwards, they filled out SGRQ, and scores were compared with clinical and radiological findings, and also with serum markers of the disease. Mean activity score values were significantly lower in men, in patients with newly diagnosed disease, and in patients with elevated ACE. Patients with extrathoracic disease had significantly higher scores. Clinical course showed significant correlation with impact and total score, and the number of relapses with the activity score. SGRQ scores significantly correlated with serum IgE and with most spirometric parameters. Our data revealed a high validity of SGRQ in patients with sarcoidosis and a great influence of respiratory disorders on general health-related q...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
Y-J BaeCOREA Study Group
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
Wei-xuan LuYuan-jue Zhu
Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih
Kai-Feng XuYuan-Jue Zhu
© 2021 Meta ULC. All rights reserved