Stability and mixing compatibility of dog epithelia and dog dander allergens

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Thomas J GrierRobert E Esch

Abstract

Little information or data are available concerning the stability and compatibility of dog epithelia and dog dander allergens. To determine the immunochemical reactivities of commercial, nonstandardized dog epithelia and dog dander extracts after exposures to various temperatures or after mixing with high-protease fungal and cockroach extracts at concentrations recommended for maintenance immunotherapy (IT) injections. Quantitative enzyme-linked immunosorbent assay and qualitative (immunoblot) analyses were performed to compare specific compositional changes with total or individual allergen activities. Assays for dog allergens Can f 1 and Can f 3 (albumin) used specific mouse or rabbit antibodies. Multiallergen enzyme-linked immunosorbent assay inhibition and immunoblot methods were conducted using a human serum pool with high levels of IgE to dog allergens. Dog allergen recoveries ranged from 22% to 134% after short exposures to moderate or extreme temperatures and from 28% to 118% after mixing with fungal or insect extracts and storage for up to 15 months at 2 degrees C to 8 degrees C. Recoveries in dog dander extracts varied up to 2.5-fold with different test methods. Immunoblots revealed partial degradation of dog albumin ...Continue Reading

References

Jun 1, 1976·The Journal of Allergy and Clinical Immunology·J L OhmanF C Lowell
Dec 1, 1991·The Journal of Allergy and Clinical Immunology·C SchouH Løwenstein
May 1, 1991·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C SchouH Løwenstein
Jan 1, 1991·International Archives of Allergy and Applied Immunology·S SpitzauerD Kraft
Mar 1, 1989·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A W FordD M Kemeny
Mar 1, 1994·The Journal of Allergy and Clinical Immunology·S SpitzauerH Rumpold
Jan 1, 1993·International Archives of Allergy and Immunology·S SpitzauerH Rumpold
Feb 4, 1999·Allergy·G CainA Woodcock
Feb 12, 2000·The Journal of Allergy and Clinical Immunology·B PandjaitanS Spitzauer
Dec 1, 2001·Clinical Reviews in Allergy & Immunology·T J Grier
Dec 1, 2001·Clinical Reviews in Allergy & Immunology·K S Morrow, J E Slater
Feb 10, 2004·The Journal of Allergy and Clinical Immunology·Robert E Esch
Aug 28, 2007·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Thomas J GrierRobert E Esch
Oct 6, 2007·The Journal of Allergy and Clinical Immunology·UNKNOWN Joint Task Force on Practice ParametersUNKNOWN Joint Council of Allergy, Asthma and Immunology
May 14, 2008·Current Opinion in Otolaryngology & Head and Neck Surgery·Greg Plunkett
Feb 12, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Tonya S RansMichael S Tankersley

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Citations

Dec 15, 2015·Expert Review of Clinical Pharmacology·Emmanuel NonyPhilippe Moingeon
Apr 4, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jay PortnoyJohn Oppenheimer
Mar 1, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Thomas J Grier
Jan 18, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Derek M Smith, Christopher A Coop
May 3, 2011·Immunology and Allergy Clinics of North America·Robert E Esch, Thomas J Grier
Jan 13, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Desiree Larenas-LinnemannUNKNOWN Environmental Allergens Workgroup
Nov 3, 2015·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Thomas J GrierSatyen M Gada
Mar 28, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Thomas J GrierKevin E Renahan
Dec 14, 2011·The Journal of Allergy and Clinical Immunology·Satyen GadaMichael Nelson
Jan 13, 2015·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Thomas J GrierTerrance C Coyne
Apr 20, 2016·Current Opinion in Otolaryngology & Head and Neck Surgery·Greg Plunkett
May 26, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Thomas J GrierTerrance C Coyne
Apr 11, 2015·Allergy & Rhinology·Barbara J Daigle, Donna J Rekkerth
Dec 3, 2010·The Journal of Allergy and Clinical Immunology·Linda CoxDana Wallace

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