Stability of β-carotene in protein-stabilized oil-in-water delivery systems

Journal of Agricultural and Food Chemistry
Leonardo Cornacchia, Yrjö H Roos


Inclusion of liposoluble bioactive compounds in fortified foods represents a complex challenge due to the labile nature of such compounds and the instability of oil-in-water emulsion-based delivery systems. In the present study, dispersions prepared with 10% (w/w) sunflower oil (SO) or hydrogenated palm kernel oil (HPKO) containing 0.05% (w/w) β-carotene were stabilized by various concentrations of whey protein isolate (WPI) or sodium caseinate (NaCas) (0.1 to 2.0% w/w) in 30% (w/w) sucrose aqueous solutions. Physicochemical characterization of emulsions was done considering the particle size, the particle surface protein coverage, and the physical state of continuous and dispersed phases. Physical stability of the systems and their protection properties on β-carotene were compared. The lipid carrier type and interfacial structure were investigated as the two key factors which regulate the stability of labile lipophilic bioactive molecules in food model systems. Our results showed high β-carotene stability when O/W systems were stable (protein concentration ≥0.8% w/w.) A (partially) solid lipid carrier (HPKO) enhanced protection compared to the liquid carrier (SO) as the bioactive molecules were entrapped in isolated domains wi...Continue Reading


Jul 1, 1970·The Journal of Organic Chemistry·A H el-Tinay, C O Chichester
Nov 11, 1999·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·A Tavani, C La Vecchia
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Sep 3, 2002·Advanced Drug Delivery Reviews·Ashutosh ChilkotiDrazen Raucher
Feb 20, 2003·Journal of Agricultural and Food Chemistry·Min HuEric Andrew Decker
Mar 6, 2003·Journal of Agricultural and Food Chemistry·Min HuEric Andrew Decker
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Oct 29, 2005·Advances in Colloid and Interface Science·D ClausseC Dalmazzone
Nov 24, 2005·Journal of Agricultural and Food Chemistry·Saori OkudaEric Andrew Decker
Jul 3, 2007·Advanced Drug Delivery Reviews·R H MüllerJ Pardeike
Feb 27, 2008·Journal of Food Science·A HentschelT Kurz
May 17, 2006·Journal of Agricultural and Food Chemistry·Parita ThanasukarnDavid Julian McClements
Aug 21, 2009·Journal of Agricultural and Food Chemistry·Thrandur HelgasonJochen Weiss
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