Stability of frozen rat plasma containing different antibiotics.

Antimicrobial Agents and Chemotherapy
M A Berti, M Maccari

Abstract

The antibiotic activity was determined at different intervals of time on plasma samples, taken from rats treated with a certain number of commonly used antibiotics, and kept at -20 C up to 8 weeks. The results of the microbiological assays demonstrate that the stability of the antibiotics in the frozen plasma decreases in the following order: oxytetracycline > cephalexin, streptomycin, erythromycin > demeclocycline > ampicillin, amoxycillin > penicillin G, cephaloridine, rolitetracycline, and tetracycline.

References

May 1, 1972·Journal of Pharmaceutical Sciences·E J Kuchinskas, G N Levy
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Apr 1, 1969·Journal of Pharmaceutical Sciences·J P Hou, J W Poole

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Citations

Jan 1, 1977·Antimicrobial Agents and Chemotherapy·M A Foglesong
Jan 1, 1981·Journal of Biomedical Materials Research·L W SwensonR l Piziali
Feb 1, 1983·Journal of Pharmacokinetics and Biopharmaceutics·P H HinderlingW Gau
Dec 24, 2014·Journal of Cataract and Refractive Surgery·Aline P de MirandaRichard Y Hida

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