Sep 22, 2011

Stability of the factorial structure of metabolic syndrome from childhood to adolescence: a 6-year follow-up study

Cardiovascular Diabetology
Vicente Martínez-VizcaínoM Sjöström

Abstract

Metabolic syndrome (MS) is a clustering of cardiometabolic risk factors that is considered a predictor of cardiovascular disease, type 2 diabetes and mortality. There is no consistent evidence on whether the MS construct works in the same way in different populations and at different stages in life. We used confirmatory factor analysis to examine if a single-factor-model including waist circumference, triglycerides/HDL-c, insulin and mean arterial pressure underlies metabolic syndrome from the childhood to adolescence in a 6-years follow-up study in 174 Swedish and 460 Estonian children aged 9 years at baseline. Indeed, we analyze the tracking of a previously validated MS index over this 6-years period. The estimates of goodness-of-fit for the single-factor-model underlying MS were acceptable both in children and adolescents. The construct stability of a new model including the differences from baseline to the end of the follow-up in the components of the proposed model displayed good fit indexes for the change, supporting the hypothesis of a single factor underlying MS component trends. A single-factor-model underlying MS is stable across the puberty in both Estonian and Swedish young people. The MS index tracks acceptably fro...Continue Reading

Mentioned in this Paper

Prevalence Studies
Arterial Pulse Pressure
Diabetes Mellitus, Non-Insulin-Dependent
Diastolic Blood Pressure Measurement
Menopause
Incidence Studies
Cardiovascular Diseases
Longitudinal Survey
Metabolic Syndrome X
Factor Analysis, Statistical

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