Stability of toxigenicity in proteolytic Clostridium botulinum type B upon serial passage

Microbiology and Immunology
Kaoru UmedaShunji Kozaki

Abstract

Proteolytic Clostridium botulinum type B strains were investigated for stability of toxigenicity and bont/b gene upon serial passage. Strains with bont/b gene located on their plasmids showed loss or decrease of toxigenicity during serial passage. Some strains lost the bont/b gene-encoding plasmid. The stability of the plasmids varied between strains.

References

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Citations

Oct 15, 2014·Research in Microbiology·Theresa J SmithBrian H Raphael
Mar 19, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Kaoru UmedaShunji Kozaki
May 12, 2018·Toxins·Domenico Azarnia Tehran, Marco Pirazzini
May 22, 2019·Microbiology Spectrum·Sarah A Revitt-MillsVicki Adams

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