Stable dynamics of pneumococcal carriage over a decade in the pre-PCV era

Vaccine
Bradley G WagnerR Dagan

Abstract

Streptococcus pneumoniae (SP) nasopharyngeal carriage studies are important to understand SP circulation prior to implementation of vaccination programs. It is generally not known how stable these carriage rates are over time. Carriage studies were conducted in Southern Israel during a decade preceding Pneumococcal Conjugate Vaccine (PCV) introduction. We estimated total and vaccine-type SP carriage at 6 months of age to be stable at 35% (95% CI: 26, 44) and 19% (95% CI: 15, 24), respectively in Jewish and 70% (95% CI, 62, 77) and 41% (95% CI: 38, 45) in Bedouin populations. The stability of carriage rates in two disparate populations over 10 years suggests a single survey may be sufficient to characterize pneumococcal carriage pre-PCV.

Citations

Jan 29, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ron DaganNoga Givon-Lavi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
A RocaRichard A Adegbola
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Philip C HillRichard A Adegbola
Archives of Pediatrics & Adolescent Medicine
Jocelyn Y AngEunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
© 2021 Meta ULC. All rights reserved