journal cover

Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA

Nucleic Acids Research

Feb 6, 2015

Anitha D JayaprakashR Sachidanandam

Abstract

Eukaryotic cells carry two genomes, nuclear (nDNA) and mitochondrial (mtDNA), which are ostensibly decoupled in their replication, segregation and inheritance. It is increasingly appreciated that heteroplasmy, the occurrence of multiple mtDNA haplotypes in a cell, plays an important bio...read more

Mentioned in this Paper

Genome
DNA, Mitochondrial
Coculture Techniques
Cell Division
Extracellular Space
Virus Replication
Nucleic Acid Sequencing
Genetic Inheritance
Sequencing
Mitochondria
4
2
99
Paper Details
References
  • References53
  • Citations8
12345...
  • References53
  • Citations8
1

Similar Papers Found In These Feeds

Non-coding Variants in Cancer

Mutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.

Non-coding Variants in Cancer (Keystone)

Mutations, single nucleotide variants and large genomic rearrangements in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. This feed focuses on the latest research on non-coding variants in cancer.

Related Papers

Fertility and Sterility

Mitochondrial DNA heteroplasmy after human ooplasmic transplantation

Fertility and SterilitySeptember 26, 2000
C A BrennerJ Cohen
Methods in Molecular Biology

Single-cell analysis of mitochondrial DNA

Methods in Molecular BiologyJanuary 30, 2015
Brendan A I PaynePatrick F Chinnery
© 2020 Meta ULC. All rights reserved

Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA

Nucleic Acids Research

Feb 6, 2015

Anitha D JayaprakashR Sachidanandam

PMID: 25653158

DOI: 10.1093/nar/gkv052

Abstract

Eukaryotic cells carry two genomes, nuclear (nDNA) and mitochondrial (mtDNA), which are ostensibly decoupled in their replication, segregation and inheritance. It is increasingly appreciated that heteroplasmy, the occurrence of multiple mtDNA haplotypes in a cell, plays an important bio...read more

Mentioned in this Paper

Genome
DNA, Mitochondrial
Coculture Techniques
Cell Division
Extracellular Space
Virus Replication
Nucleic Acid Sequencing
Genetic Inheritance
Sequencing
Mitochondria
4
2
99

Similar Papers Found In These Feeds

Non-coding Variants in Cancer

Mutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.

Non-coding Variants in Cancer (Keystone)

Mutations, single nucleotide variants and large genomic rearrangements in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. This feed focuses on the latest research on non-coding variants in cancer.

Related Papers

Fertility and Sterility

Mitochondrial DNA heteroplasmy after human ooplasmic transplantation

Fertility and SterilitySeptember 26, 2000
C A BrennerJ Cohen
Methods in Molecular Biology

Single-cell analysis of mitochondrial DNA

Methods in Molecular BiologyJanuary 30, 2015
Brendan A I PaynePatrick F Chinnery
Paper Details
References
  • References53
  • Citations8
12345...
  • References53
  • Citations8
1
/papers/stable-heteroplasmy-at-the-single-cell-level-is/25653158