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Stable heteroplasmy at the single cell level is facilitated by inter-cellular exchange of mtDNA

bioRxiv

Jul 10, 2014

Anitha Devi JayaprakashRavi Sachidanandam

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Abstract

Eukaryotic cells carry two genomes, nuclear (nDNA) and mitochondrial (mtDNA), which are ostensibly decoupled in their replication, segregation and inheritance. It is increasingly appreciated that heteroplasmy, the occurrence of multiple mtDNA haplotypes in a cell, plays an important bio...read more

Mentioned in this Paper

Extracellular Space
Coculture Techniques
Mitochondrial DNA Location
Genome
Virus Replication
Cell Division
Mitochondria
Colony (Cells or Organisms)
Exchanger
Nucleic Acid Sequencing
7
10
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  • Stable heteroplasmy at the single cell level is facilitated by inter-cellular exchange of mtDNA

    bioRxiv

    Jul 10, 2014

    Anitha Devi JayaprakashRavi Sachidanandam

    PMID: 990007005

    DOI: 10.1101/007005

    Abstract

    Eukaryotic cells carry two genomes, nuclear (nDNA) and mitochondrial (mtDNA), which are ostensibly decoupled in their replication, segregation and inheritance. It is increasingly appreciated that heteroplasmy, the occurrence of multiple mtDNA haplotypes in a cell, plays an important bio...read more

    Mentioned in this Paper

    Extracellular Space
    Coculture Techniques
    Mitochondrial DNA Location
    Genome
    Virus Replication
    7
    10

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