Stable Ischemic Heart Disease

Annals of Internal Medicine
Daniel Katz, Michael C Gavin

Abstract

Stable ischemic heart disease (SIHD) is a leading cause of death in the United States and many other countries. The defining pathobiology is an imbalance between the metabolic demands of the myocardium and its oxygen supply, which most often results from coronary artery atherosclerosis. The classic presenting symptom of SIHD is angina, but clinical presentation varies greatly among patients. Since the last In the Clinic on SIHD in 2014, several new drugs have been approved to reduce ischemic complications, such as myocardial infarction and congestive heart failure.

References

Jun 14, 1979·The New England Journal of Medicine·G A Diamond, J S Forrester
Aug 1, 1991·The New England Journal of Medicine·UNKNOWN SOLVD InvestigatorsJay N Cohn
Nov 1, 1990·The American Review of Respiratory Disease·J M Samet
Jul 15, 1990·Annals of Internal Medicine·C B TaylorR F DeBusk
Jun 1, 1987·Annals of Internal Medicine·D B MarkD B Pryor
Jun 1, 1999·JAMA : the Journal of the American Medical Association·P A HeidenreichM A Hlatky
Jan 20, 2000·The New England Journal of Medicine·UNKNOWN Heart Outcomes Prevention Evaluation Study InvestigatorsG Dagenais
Jan 5, 2002·The New England Journal of Medicine·B G BrownJ J Albers
Mar 20, 2003·Journal of the American College of Cardiology·Sonia S Anand, Salim Yusuf
Jan 22, 2005·American Heart Journal·Gilles R DagenaisSalim Yusuf
Aug 1, 2006·Journal of the American College of Cardiology·Peter H StoneUNKNOWN ERICA Investigators
Jun 8, 2007·The New England Journal of Medicine·Earl S FordSimon Capewell
Mar 29, 2008·Journal of the American College of Cardiology·Joel E Dimsdale
Nov 11, 2008·European Heart Journal·Cinta de DiegoUNKNOWN EPIVAC Study Group
Dec 10, 2008·The American Journal of Clinical Nutrition·Robyn L McClellandUNKNOWN Multi-Ethnic Study of Atherosclerosis
Feb 21, 2009·The New England Journal of Medicine·Patrick W SerruysUNKNOWN SYNTAX Investigators
Mar 6, 2012·Clinical Cardiology·Martha GulatiC Noel Bairey Merz
Sep 8, 2012·Journal of the American College of Cardiology·Mario MarzilliWilliam S Weintraub
Nov 6, 2012·The New England Journal of Medicine·Michael E FarkouhUNKNOWN FREEDOM Trial Investigators
Mar 28, 2013·JAMA : the Journal of the American Medical Association·Gervasio A LamasUNKNOWN TACT Investigators
Jun 26, 2013·The New England Journal of Medicine·Rena R WingSusan Z Yanovski
Aug 2, 2013·Diabetes Care·Vojtech Hainer, Irena Aldhoon-Hainerová
Nov 28, 2013·JAMA Internal Medicine·Maria Rubini GimenezChristian Mueller
May 7, 2014·Annals of Internal Medicine·Stephen P FortmannBrittany U Burda
Feb 14, 2015·JACC. Cardiovascular Imaging·Mark A MarinescuJamieson M Bourque
Mar 17, 2015·The New England Journal of Medicine·Pamela S DouglasUNKNOWN PROMISE Investigators
Nov 10, 2015·The New England Journal of Medicine·UNKNOWN SPRINT Research GroupWalter T Ambrosius
Aug 30, 2016·The New England Journal of Medicine·R Doug McEvoyUNKNOWN SAVE Investigators and Coordinators
May 26, 2017·The New England Journal of Medicine·Jeffrey L Anderson, David A Morrow
Aug 19, 2017·Journal of the American College of Cardiology·Raphael TwerenboldChristian Mueller

❮ Previous
Next ❯

Citations

Dec 4, 2019·Annals of Internal Medicine·Richmond Doxey
Jun 12, 2021·Cardiovascular Toxicology·Shafreena Shaukat AliWan Amir Nizam Wan Ahmad

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
gastric bypass
coronary artery bypass
pharmacotherapy

Software Mentioned

SPRINT
MedlinePlus

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.