Stable lead isotopes in environmental health with emphasis on human investigations

The Science of the Total Environment
B L Gulson

Abstract

There has been widespread use of stable lead isotopes in the earth sciences for more than 40 years focussed on the origin and age of rocks and minerals with lesser application in environmental investigations where the emphasis has been directed typically to the source of lead in environmental media such as air, water and soils. In contrast, the number of environmental health investigations focussed on humans (and primates) is limited in spite of the demonstrated utility of the approach in pioneering studies in the early 1970's. This paper reviews the status of lead isotopes in human investigations especially over the past 2 decades, the period over which most activity has taken place. Following a brief introduction to the method, examples are provided illustrating the use of lead isotopes in a wide spectrum of activities including sources and pathways of lead in diverse environments from urban to mining communities, various applications associated with pregnancy, the contribution of bone lead to blood lead including in the elderly, the half-life of lead in blood, and lead in bones and other media. A brief outline of critical research on non-human primates is also given. The lead isotope method is a powerful technique for tracin...Continue Reading

References

Aug 1, 1976·The Journal of Clinical Investigation·M B RabinowitzJ D Kopple
Jul 1, 1977·Archives of Environmental Health·W I Manton
Jul 1, 1976·Archives of Environmental Health·M RabinowitzJ Kopple
Sep 1, 1992·British Journal of Industrial Medicine·W I Manton
Sep 1, 1991·The Science of the Total Environment·M Manea-KrichtenY Erel
Sep 1, 1991·The Science of the Total Environment·C PattersonH Shirahata
Feb 1, 1991·Environmental Health Perspectives·M B Rabinowitz
Nov 1, 1990·Environmental Health Perspectives·R A Goyer
Apr 1, 1990·The Science of the Total Environment·S Facchetti
Mar 1, 1986·Journal of Epidemiology and Community Health·A J McMichaelP D Clark
Mar 1, 1985·British Journal of Industrial Medicine·W I Manton
Mar 1, 1985·Archives of Environmental Health·O TeraT R Watkins
Nov 16, 1973·Science·M B RabinowitzJ D Kopple
May 1, 1974·Environmental Health Perspectives·M RabinowitzJ D Kopple
Sep 1, 1969·Journal of the Air Pollution Control Association·R A Kehoe
Aug 1, 1984·British Journal of Industrial Medicine·W I Manton, J D Cook
Feb 1, 1983·British Journal of Industrial Medicine·W I Manton, C R Malloy
Jul 1, 1983·Archives of Environmental Health·Y YaffeG C Coleman
Mar 14, 1980·Science·D M Settle, C C Patterson
Jun 25, 1982·Science·M B Rabinowitz, H L Needleman
May 2, 1994·The Science of the Total Environment·J L StauberL S Dale
Jul 1, 1994·Archives of Environmental Health·B Gulson, D Wilson
Mar 1, 1993·Annals of Clinical Biochemistry·I A al-SalehA Taylor
Jan 1, 1995·Journal of Toxicology. Clinical Toxicology·C R AngleK L Stanek
Feb 1, 1996·Environmental Health Perspectives·J H GrazianoM R Moore
Jan 1, 1996·Environmental Health Perspectives·D R SmithA R Flegal
Oct 11, 1996·The Science of the Total Environment·B L GulsonD Howarth
Mar 1, 1996·Environmental Health Perspectives·B L Gulson
Oct 1, 1996·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·M J InskipE B Edwards
Jul 1, 1997·The Journal of Laboratory and Clinical Medicine·B L GulsonG Vimpani
Nov 5, 1997·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·C A FranklinE J O'flaherty
Aug 1, 1997·Environmental Health Perspectives·B L Gulson, B R Gillings
Feb 28, 1998·Environmental Health Perspectives·B L GulsonM J Korsch
May 14, 1998·The Journal of Laboratory and Clinical Medicine·B L GulsonJ A Eisman

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Citations

Nov 24, 2012·Chemistry Central Journal·Elise DeshommesMichèle Prévost
Feb 26, 2016·Forensic Science International : Synergy·Austin T KellerNathan W Bower
Aug 16, 2014·Environment International·Suzhen CaoGuibin Jiang
Jan 12, 2016·Journal of Agricultural and Food Chemistry·Paola ManiniAlessandra Napolitano
Sep 21, 2011·The Science of the Total Environment·John G FarmerRichard J F Bewley
May 10, 2011·The Science of the Total Environment·Kuria Ndung'uA Russell Flegal
Mar 7, 2009·The Science of the Total Environment·Vernon G ThomasDella E Bond
Jun 8, 2014·The Science of the Total Environment·George D Kamenov, Brian L Gulson
Jan 13, 2015·Science & Justice : Journal of the Forensic Science Society·Geneviève VautourDavid Widory
Jan 13, 2015·Science & Justice : Journal of the Forensic Science Society·Laura FontGareth R Davies
Dec 21, 2016·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Rebeca Y Pérez-RodríguezFernando Díaz-Barriga
Jan 22, 2017·The Science of the Total Environment·Analine Berenice Vázquez BahénaGerardo Huerta Beristain
Apr 12, 2018·International Journal of Environmental Research and Public Health·Brian GulsonMichael Rabinowitz
Feb 2, 2018·Scientific Reports·Jane EvansCarolyn Chenery
Mar 28, 2019·Forensic Sciences Research·Eric J Bartelink, Lesley A Chesson
Sep 26, 2019·Frontiers in Veterinary Science·Amanda H BoesenJon M Arnemo
Feb 3, 2021·The Science of the Total Environment·Efstratios KelepertzisAriadne Argyraki
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Cathleen L Doherty, Brian T Buckley
May 20, 2021·Forensic Sciences Research·Laura A ReganMatthew D Cooney
Sep 19, 2019·Environmental Science & Technology·Jenna E ForsythStephen P Luby
Dec 6, 2021·The Science of the Total Environment·Katerina RodiouchkinaFrank Vanhaecke

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