PMID: 6169010Aug 11, 1981Paper

Stable RNA synthesis and its control in Mycoplasma capricolum

Nucleic Acids Research
G GlaserS Razin

Abstract

The synthesis of stable RNA in Mycoplasma capricolum was studied by [32P] labeling of cellular RNA of cells grown in a partially-defined medium in the presence or absence of an amino acid mixture supplement. The results indicate that M. capricolum employs the same stringent control mechanism used by E. coli cells, as judged by a decreased synthesis of stable RNA and accumulation of 5'-triphosphoguanosine-3'-diphosphate (pppGpp) and 5'-diphosphoguanosine-3'-diphosphate (ppGpp) in response to amino acid starvation. In addition, the results suggest that precursors of stable RNA accumulate and an intracellular pool of the precursors exists at all times under the growth conditions used by us. These findings may be interpreted to reflect a slow rate of RNA processing in M. capricolum.

References

Jan 1, 1975·Annual Review of Microbiology·M Cashel

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Citations

Jul 24, 1982·Nucleic Acids Research·D AmikamG Glaser
Mar 12, 1984·Nucleic Acids Research·G GlaserS Razin
Aug 19, 2009·Antimicrobial Agents and Chemotherapy·Mikkel A AlgireChuck Merryman
May 29, 2010·Microbiology and Molecular Biology Reviews : MMBR·Zachary D DalebrouxMichele S Swanson
Jul 1, 1988·Journal of Bacteriology·H C HymanS Razin

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