Stage I endometrial carcinoma

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
K PeignauxP Maingon

Abstract

Most endometrial cancers are diagnosed at stage I (disease limited to the uterine corpus). The definitive treatment for endometrial carcinoma consists in total abdominal hysterectomy and bilateral salpingo-oophorectomy with or without lymphadenectomy. The decision of adjuvant treatment depends on risk factors. Postoperative radiotherapy plays a major role in the management of stage I endometrial cancer but the respective place of external radiotherapy and vaginal brachytherapy remains controversial. Adjuvant external beam radiotherapy reduces locoregional recurrences, but carries a risk of toxicity without overall survival benefits. Recent data suggest that vaginal brachytherapy is effective in preventing vaginal recurrence with lower toxicity and should be the treatment of choice for intermediate risk endometrial cancer.

References

Mar 10, 1998·Obstetrics and Gynecology·D M LarsonB R Krawisz
Dec 30, 1998·International Journal of Radiation Oncology, Biology, Physics·C MacLeodJ Carter
Jun 28, 2000·American Journal of Obstetrics and Gynecology·A MarianiK C Podratz
Jun 14, 2002·International Journal of Radiation Oncology, Biology, Physics·Kaled M AlektiarRichard R Barakat
Aug 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Kaled M AlektiarRichard R Barakat
Mar 31, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Carien L CreutzbergUNKNOWN postoperative Radiation Therapy in Endometrial Carcinoma Trial
Dec 8, 2004·Gynecologic Oncology·William T CreasmanPeter Boyle
Jul 21, 2005·International Journal of Radiation Oncology, Biology, Physics·Matthew C SolhjemMichael G Haddock
Oct 4, 2005·International Journal of Radiation Oncology, Biology, Physics·Chad A HamiltonJohn K Chan
Apr 25, 2006·Gynecologic Oncology·Himu LukkaJanice Kwon
Sep 1, 2007·Current Opinion in Oncology·Frederic AmantIgnace Vergote
Sep 7, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·N Johnson, P Cornes
Apr 29, 2008·Clinical Oncology : a Journal of the Royal College of Radiologists·C M Holland
May 6, 2008·Clinical Oncology : a Journal of the Royal College of Radiologists·A KongP Blake
May 9, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M M BaekelandtUNKNOWN ESMO Guidelines Working Group
Jul 2, 2008·Obstetrics and Gynecology·Angie D Yong, Giuseppe Del Priore

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.