Stage III and IV ovarian cancer in the South West of England: five-year outcome analysis for cases treated in 1998

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
J BaileyC Foy

Abstract

This study evaluates the 5-year outcome data for the management of advanced ovarian cancer in the South West of England. Anonymized data for 361 stage III and IV ovarian cancers registered between January 1, 1998, and December 31, 1998, were obtained from the central gynecological tumor database. The following data were identified: age at diagnosis, FIGO stage, American Society of Anesthesiologists (ASA) grade, tumor differentiation, treating network and surgeon, amount of residual disease after debulking surgery, current life status, and date of death if applicable. Survival analysis was performed using Kaplan-Meier crude survival for univariate analysis, and multivariate analysis was performed by Cox regression. In our data the 5-year survival for patients with stage III was 16% and with stage IV was 10%. Survival analysis demonstrated that patients in whom the disease was debulked to less than 1 cm were more likely to be alive 5 years after diagnosis than those with a 2-cm residuum (P < 0.0001). There was no significant survival difference for those patients operated on by subspecialist surgeons despite these surgeons being twice as likely to achieve optimal debulking. Therefore, there must be other variables influencing sur...Continue Reading

References

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Citations

May 30, 2012·Obstetrics and Gynecology Clinics of North America·Clare Reade, Laurie Elit
Mar 8, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G LyratzopoulosD Greenberg
Jun 29, 2010·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·L VerleyeA G J van der Zee
Sep 1, 2009·Gynecologic Oncology·Talia FosterThomas J Herzog
Sep 3, 2013·Gynecologic Oncology·Elfriede GreimelUNKNOWN European Organization for Research and Treatment of Cancer - Gynaecological Cancer Group and NCIC Clinical Trials Group
Oct 20, 2012·Developmental Biology·Ashwini Balakrishnan, J Richard Chaillet
Mar 16, 2012·The Cochrane Database of Systematic Reviews·Yin Ling WooHeather O Dickinson
Aug 13, 2011·The Cochrane Database of Systematic Reviews·Ahmed ElattarRaj Naik
Apr 21, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·B Van CalsterS Van Huffel
Mar 5, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Christian MarthPaul Sevelda

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