Staging and surgical approaches in gastric cancer: a clinical practice guideline

Current Oncology
N CoburnJ Ringash

Abstract

Resection is the cornerstone of cure for gastric adenocarcinoma; however, several aspects of surgical intervention remain controversial or are suboptimally applied at a population level, including staging, extent of lymphadenectomy (lnd), minimum number of lymph nodes that have to be assessed, gross resection margins, use of minimally invasive surgery, and relationship of surgical volumes with patient outcomes and resection in stage iv gastric cancer. Literature searches were conducted in databases including medline (up to 10 June 2016), embase (up to week 24 of 2016), the Cochrane Library and various other practice guideline sites and guideline developer Web sites. A practice guideline was developed. One guideline, seven systematic reviews, and forty-eight primary studies were included in the evidence base for this guidance document. Seven recommendations are presented. All patients should be discussed at a multidisciplinary team meeting, and computed tomography (ct) imaging of chest and abdomen should always be performed when staging patients. Diagnostic laparoscopy is useful in the determination of M1 disease not visible on ct images. A D2 lnd is preferred for curative-intent resection of gastric cancer. At least 16 lymph no...Continue Reading

Citations

Nov 7, 2019·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Jordan LevyUNKNOWN PRESTO Group
Sep 25, 2019·Annals of Gastroenterological Surgery·Takeo Fukagawa
Mar 22, 2021·World Journal of Surgical Oncology·Elizabeth JacobAyana Allard-Picou
Jun 1, 2021·Gastrointestinal Endoscopy Clinics of North America·Ian Solsky, Haejin In
Apr 24, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Jiapeng DanFang Li

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