Staging of invasive cervical carcinoma and of pelvic lymph nodes by high resolution MRI with a phased-array coil in comparison with pathological findings
Abstract
Our goal was to stage invasive cervical carcinoma (pT1b-pT4a) and pelvic lymph nodes by high resolution MRI with a circularly polarized (cp) phased-array coil in correlation with the whole-mount specimen and the histopathological findings. Thirty-three patients (20-68 years old; mean age 55 years) with biopsy-proven primary cancer of the cervix were prospectively examined on a 1.5 T scanner by using a cp body phased-array coil. The MR protocol consisted of high resolution T2-weighted turbo-SE (TSE) and pre- and postcontrast T1-weighted SE (SE) sequences. Slice thickness was 5-7 mm with a pixel size of 0.3-0.4 mm2. All MRI findings were matched to the whole-mount specimens and the histopathological findings. Pathological stages evaluated were pT1b (n = 5), pT2b (n = 16), and pT4a (n = 12). The overall accuracy rates for tumor staging were 79% for high resolution T2-weighted TSE and 76% for postcontrast T1-weighted SE images. The accuracy for high resolution T2-weighted TSE images in determining parametrial infiltration, pelvic side wall, and bladder and rectal wall infiltration was 84, 87, and 87%, respectively. In prospective analysis of the 1.0 cm criterion for diagnosis of a positive pelvic lymph node, MRI had a 72% accuracy,...Continue Reading
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