Standard care quality determines treatment outcomes in control groups of HAART-adherence intervention studies: implications for the interpretation and comparison of intervention effects

Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association
Marijn de BruinGerjo Kok

Abstract

Clinical trials of behavioral interventions seek to enhance evidence-based health care. However, in case the quality of standard care provided to control conditions varies between studies and affects outcomes, intervention effects cannot be directly interpreted or compared. The objective of the present study was to examine whether standard care quality (SCQ) could be reliably assessed, varies between studies of highly active antiretroviral HIV-adherence interventions, and is related to the proportion of patients achieving an undetectable viral load ("success rate"). Databases were searched for relevant articles. Authors of selected studies retrospectively completed a checklist with standard care activities, which were coded to compute SCQ scores. The relationship between SCQ and the success rates was examined using meta-regression. Cronbach's alpha, variability in SCQ, and relation between SCQ and success rate. Reliability of the SCQ instrument was high (Cronbach's alpha = .91). SCQ scores ranged from 3.7 to 27.8 (total range = 0-30) and were highly predictive of success rate (p = .002). Variation in SCQ provided to control groups may substantially influence effect sizes of behavior change interventions. Future trials should th...Continue Reading

Citations

Jun 19, 2013·Health Psychology Review·Gjalt-Jorn Ygram PetersGerjo Kok
Sep 18, 2012·Implementation Science : IS·Anita HuisMarlies Hulscher
Mar 21, 2013·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Susan MichieCaroline E Wood
Aug 12, 2015·Health Psychology Review·Gerjo KokL Kay Bartholomew
Apr 11, 2015·Current Infectious Disease Reports·Sharon Mannheimer, Yael Hirsch-Moverman
Aug 21, 2014·Psychology & Health·Silvia M A A EversCharles Christian Adarkwah
Nov 15, 2011·The Journal of the Association of Nurses in AIDS Care : JANAC·Jennifer L PetersonJudith L Neidig
Apr 23, 2016·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Seth C KalichmanRaymond F Schinazi
Nov 1, 2016·Health Psychology Review·Lenneke van GenugtenPepijn van Empelen
Jan 22, 2013·Journal of the International Association of Providers of AIDS Care·K Rivet Amico, Catherine Orrell
Jun 10, 2015·Journal of the International Association of Providers of AIDS Care·Lina BofillDeborah Jones
Jul 12, 2017·The International Journal of Behavioral Nutrition and Physical Activity·Carol Byrd-BredbennerYingting Zhang
Mar 14, 2014·Western Journal of Nursing Research·Judith A ErlenHonghu Liu
Mar 27, 2018·Health Psychology Review·G J MolloyJ Newell
May 27, 2016·The Cochrane Database of Systematic Reviews·Rachael PowellMarie Johnston
Jun 19, 2018·Health Psychology Review·Sarah Ellen GriffithsKatherine E Brown
May 1, 2010·The Journal of the Association of Nurses in AIDS Care : JANAC·Sigrid C J M VervoortAndy I M Hoepelman

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