Standard Guidelines of Care: Performing Procedures in Patients on or Recently Administered with Isotretinoin

Journal of Cutaneous and Aesthetic Surgery
Venkataram MysoreAnil Ganjoo

Abstract

Currently, the standard protocol regarding the performance of procedures on patients receiving or having recently received isotretinoin (13-cis-retinoic acid) states that the procedures should not be performed. The recommendations in standard books and drug insert require discontinuation of isotretinoin for 6 months before performing cosmetic procedures, including waxing, dermabrasion, chemical peels, laser procedures, or incisional and excisional cold-steel surgery. These recommendations have been followed for over two decades despite little evidence for the stated increased risk of scarring. The Association of Cutaneous Surgeons (I) constituted a task force to review the evidence and to recommend consensus guidelines regarding the safety of skin procedures, including resurfacing, energy-device treatments, and dermatosurgical procedures in patients with concurrent or recent isotretinoin administration. Data were extracted from the literature through a PubMed search using the keywords "isotretinoin," "safety," "scarring," "keloids," "hypertrophic scarring," and "pigmentation." The evidence was then labeled and circulated to all members of task force for review. The task force is of the opinion that there is insufficient evidenc...Continue Reading

References

Dec 1, 1990·The Journal of Dermatologic Surgery and Oncology·R L MoyJ Uitto
Jan 1, 1989·Archives of Dermatological Research·P J Frosch, B M Czarnetzki
Jun 10, 2000·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·H BehniaM Shahrokhi
Jul 22, 2014·International Journal of Dermatology·Byalakere Shivanna ChandrashekarMaragowdanahalli Lingegowda Rajashekar
Jul 12, 2016·Journal of Cutaneous and Aesthetic Surgery·Omprakash Heggadahalli MahadevappaAnil Ganjoo

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Citations

Aug 30, 2020·International Journal of Dermatology·Haady Fallah, Marius Rademaker
Aug 4, 2020·Expert Review of Clinical Pharmacology·Edileia Bagatin, Caroline Sousa Costa
Jun 13, 2020·American Journal of Clinical Dermatology·Tina S Alster, Monica K Li
Nov 19, 2020·Dermatologic Therapy·Natalia Gennadievna KalashnikovaMohammad Jafferany

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Methods Mentioned

BETA
biopsy

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