Staphylococcus aureus carriage in the anterior nares of close contacts of patients with atopic dermatitis

Archives of Dermatology
Lai Shan ChiuKam Lun Hon

Abstract

To study the prevalence of Staphylococcus aureus colonization in close contacts of patients with atopic dermatitis (AD) and the influence on AD severity. Prospective case-control study. Pediatric dermatology clinic in a Hong Kong university hospital. Patients We recruited 211 subjects prospectively, including 50 AD patients, 50 non-AD control subjects, 60 close contacts of AD patients, and 51 close contacts of controls. Intervention Nasal swabs and skin swabs were taken. Severity of AD was assessed using the SCORAD (Scoring Atopic Dermatitis) index. The prevalence of S aureus colonization in the close contacts of AD patients was compared with that of the close contacts of non-AD controls. Between-group differences were assessed, where appropriate, by unpaired t test or Pearson chi(2) test. Multivariate logistic regression using the forward stepwise method was performed to identify independent predictors of severe AD. A probability value of P < .05 was considered statistically significant. Significantly more nasal carriers of S aureus were found among the close contacts of AD patients (14 of 60 [23%]) than among the close contacts of non-AD controls (4 of 51 [8%] [P = .03]). The difference was still significant after the exclusi...Continue Reading

Citations

Apr 5, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Byung Soo KimDo Won Kim
Oct 20, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·R Dodiuk-GadD Rozenman
Nov 28, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Byung Soo KimDo Won Kim
Sep 17, 2015·Environmental Microbiology·Harald Brüssow
Jul 16, 2016·Clinical and Experimental Dermatology·K L HonM Ip
May 21, 2020·Journal of Medical Microbiology·Fernanda Sampaio CavalcanteKátia Regina Netto Dos Santos
Jun 8, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·A WollenbergUNKNOWN European Dermatology Forum (EDF), the European Academy of Dermatology and Venereology (EADV), the European Academy of Allerg
Nov 19, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·A WollenbergUNKNOWN European Task Force on Atopic Dermatitis/EADV Eczema Task Force
Mar 25, 2021·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Chen HuTamar Nijsten

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