Abstract
Staphylococcus aureus is a major cause of hospital-acquired infections. The ability to survive on abiotic surfaces is an important characteristic that facilitates transmission between human hosts. We found that S. aureus survivors of dry surface incubation are resistant to subsequent dry stress exposure. Survivors also had reduced sensitivity to the disinfectant chlorhexidine gluconate, but not to ethanol. By using a set of mutants in cardiolipin synthase genes, we further demonstrated that the housekeeping cardiolipin synthase, Cls2, was significant for survival on dry surface. Taken together, this study provides insights into S. aureus survival outside of a host.
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Dec 28, 2019·PloS One·Tomoko ShimodaHiroyuki Yamaguchi
Oct 4, 2017·BMC Microbiology·Yuri UshijimaKazuya Morikawa
Dec 5, 2019·Microorganisms·Kazuya MorikawaKunio Takeyasu
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