Staphylococcus aureus endocarditis in Danish intravenous drug users: high proportion of left-sided endocarditis

Scandinavian Journal of Infectious Diseases
M FaberV T Rosdahl

Abstract

In a retrospective study covering the years 1982-1989 episodes of Staphylococcus aureus endocarditis in 51 intravenous drug users were studied. Tricuspid involvement dominated (34/51), but the frequency of left-sided involvement (33.3%) was greater than in earlier reports. Involvement of both sides of the heart was not detected, but 27.8% of the left-sided endocarditis cases had multiple pulmonary infiltrates, indicating that some of them might have had a concomitant right-sided endocarditis. The 2 groups were compared: patients with left-sided endocarditis were significantly older and with a longer time of intravenous drug use. The complication rate was the same (44.1%) as was the duration of antibiotic treatment (median 42 days). In total, five patients underwent surgery, two (5.8%) due to right-sided failure and three (29.4%) because of left-sided endocarditis. The mortality of tricuspid endocarditis was low (2.9%), whereas 5 patients (29.4%) with left-sided involvement died. The patients who died were significantly older and had a shorter duration of symptoms before hospitalization.

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Citations

Nov 10, 1998·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·H HogevikR Andersson
Jul 3, 2002·Infectious Disease Clinics of North America·Hubert LepidiDidier Raoult
Aug 28, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Antonio Hernandez ConteRoya Yumul
Mar 10, 2010·Circulation·Bernard D Prendergast, Pilar Tornos
Nov 7, 2017·Infectious Diseases·Hilmir AsgeirssonOla Weiland

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