Staphylococcus aureus nasal carriage in patients on haemodialysis: role of cutaneous colonization

The Journal of Hospital Infection
C PeñaJ Ariza

Abstract

We performed a prospective study of Staphylococcus aureus nasal carriage in patients on chronic haemodialysis to determine the role of cutaneous colonization in the aetiology of recurrent nasal colonization. From February 2000 to September 2001, 71 patients on chronic haemodialysis in the dialysis unit at a university hospital were screened monthly for S. aureus nasal carriage. Carriers received nasal mupirocin for five days and were tested for nasal and cutaneous carriage two days later and monthly thereafter. Using genotyping results, recurrence was defined as relapse if pretreatment and subsequent nasal isolates were clonally identical; if the isolates were different, it was considered recolonization. Thirty-nine patients (55%) were nasal carriers: 11 initially and 28 during follow-up. Among the mupirocin-treated patients, the eradication of S. aureus nasal carriage rate was 88.5%. Nasal recurrence was documented in 17 patients (43.5%), and S. aureus nasal strains were available for molecular typing in 14 patients with a total of 23 recurrence episodes. On the basis of pulsed-field gel electrophoresis analysis, 16 (70%) recurrence episodes were considered relapses and seven were considered (30%) recolonizations. Among the ep...Continue Reading

Citations

Mar 23, 2011·Nature Reviews. Nephrology·Michiel G H Betjes
Aug 9, 2006·Seminars in Dialysis·Michel Chonchol
Nov 13, 2008·Seminars in Dialysis·Gerald A Beathard, Aris Urbanes
Sep 7, 2006·Journal of Clinical Microbiology·Peter Nilsson, Torvald Ripa
Oct 16, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Chun-Fu LaiKwan-Dun Wu
Jul 6, 2014·BMC Research Notes·Caroline Marshall, Emma McBryde
Jul 15, 2011·Médecine et maladies infectieuses·K SoulyL Benamar
Feb 22, 2011·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Lynn N FitzgibbonsGraeme N Forrest
Oct 4, 2008·Best Practice & Research. Clinical Anaesthesiology·William J MauermannRodney L Thompson
Jul 26, 2011·Microbes and Infection·María Sol BarbagelataFernanda Buzzola
Jul 21, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C-H LiaoP-R Hsueh
Sep 18, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S McNicholasD Fitzgerald-Hughes
Nov 1, 2015·BMC Infectious Diseases·Guillermo CuervoUNKNOWN REIPI/GEIH study group
Aug 26, 2006·The Journal of Hospital Infection·A KonvalinkaI W Fong
Mar 22, 2014·Journal of the American Society of Nephrology : JASN·Ioannis M ZacharioudakisEleftherios Mylonakis
May 27, 2021·International Journal of Microbiology·Arwa Mohammed OthmanHuda Zaid Al-Shami

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