PMID: 15387411Sep 25, 2004Paper

Starch-chitosan hydrogels prepared by reductive alkylation cross-linking

Journal of Materials Science. Materials in Medicine
E T BaranRui L Reis

Abstract

Starch-chitosan hydrogels were produced by oxidation of soluble starch to produce polyaldehyde and subsequently cross-linked with chitosan via reductive alkylation. The swelling ratio of starch-chitosan membranes was increased gradually with increasing starch ratio, but it was always lower than the native chitosan. In dry state, starch-chitosan membranes with low starch ratio (0.16, 0.38) showed similar tensile strength values to those of native chitosan while these values decreased with increasing starch ratios (0.73-1.36). Membranes in physiological buffer solution (PBS) gave a tensile modulus between 2.8 and 1.0 MPa, decreasing with increasing starch ratio (0.16-1.36 (Wstarch/Wchitosan)). When the membranes were incubated in PBS only, a moderate weight loss was observed for the first two weeks. Original weights of low starch weight ratio membranes (0-0.38) were at near 85%, while high ratio samples (0.73-1.55) were kept around 70% after three months. However, for the membranes incubated in alpha-amylase solution, very fast weight loss was observed. For low starch ratio membranes (0.16, 0.38, 0.73), the residual original weights were measured to be 11%, 6%, 20%, while for high ratio membranes (1.04 and 1.36) these were 45% an...Continue Reading

Citations

Oct 15, 2008·Journal of Materials Science. Materials in Medicine·M Alberta AraújoManuel Mota
Jan 23, 2009·Journal of Materials Science. Materials in Medicine·Eugenia TeodorRaluca Somoghi
Mar 5, 2009·Journal of Materials Science. Materials in Medicine·B HoffmannG Ziegler
Jan 31, 2012·Journal of Materials Science. Materials in Medicine·Ana C MendesRui L Reis
Aug 4, 2011·Tissue Engineering. Part B, Reviews·Ana Rita Costa-PintoNuno M Neves
Sep 30, 2014·Carbohydrate Polymers·Sindhuja Bala SubramanianThiyagarajan Devasena
Apr 17, 2016·Carbohydrate Polymers·Anderson Fiamingo, Sergio Paulo Campana-Filho
Dec 15, 2006·Acta Biomaterialia·Luciano F BoeselRui L Reis
May 7, 2016·Dental Materials Journal·Gang ZhouYubo Fan
May 15, 2015·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Elizabeth R BalmayorRui L Reis
Oct 7, 2016·Cytotechnology·Ya-Ching LinSheng-Chi Wu
Apr 3, 2008·Journal of Tissue Engineering and Regenerative Medicine·P C BessaR L Reis
Nov 1, 2017·Chemistry Central Journal·Tamás FeketeLászló Wojnárovits

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.