State-of-the-art of non-hormonal methods of contraception: III. Intrauterine devices

The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception
Irving Sivin, István Batár

Abstract

Since the 1959 revival of the IUD, non-hormonal devices have become the most widely used of all reversible contraceptives. Pregnancy rates of copper-releasing IUDs in current use range from approximately 0.5 to 1.5 per hundred continuing users in the first year, with somewhat lower annual pregnancy rates thereafter. Evidence-based research has been systematically conducted and translated into guidelines for eligibility criteria and problem management. Recent device research, beyond the T, Multiload and frameless devices has centred on improved designs such as U ,Y and Slimline shapes, or enhanced copper release, the latter through electrochemical effects or nanotechnology applications. Other IUD research foci concern devices that decrease bleeding and pain by releasing non-steroidal anti-inflammatory drugs. Yet other research lines indicate noncontraceptive benefits of copper intrauterine devices in protecting against endometrial cancer, and favourable risk-benefit analyses of IUD use by women at risk of or post HIV infection. IUD mechanisms of action and the relation of IUDs to pelvic infection and ectopic pregnancy are briefly reviewed. For our literature search we used Medline, Popline and Cochrane Library data bases, Google...Continue Reading

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Citations

May 8, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Ching-Hui ChenCherng-Jye Jeng
Dec 17, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Y CakirogluE Caliskan
May 19, 2011·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Annie J MiddletonNicola Singer
Apr 18, 2014·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Azam JafariRoya Torkashvand
Feb 2, 2011·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Dirk Wildemeersch
Dec 18, 2013·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Ilknur MutluMehmet Firat Mutlu
Mar 25, 2010·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·István Batár
May 6, 2010·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Xiaowen ZhouJianping Liu
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Feb 19, 2019·Clinical Practice and Cases in Emergency Medicine·Matthew R NethDavid C Pigott

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