Statin prescription is essential in peripheral vascular disease

Journal of Vascular and Interventional Radiology : JVIR
Joe J LeyonSuresh Babu

Abstract

Hypercholesterolemia is an important and easily modifiable risk factor for peripheral arterial disease (PAD), but is frequently not adequately addressed by vascular interventionists. Patients with PAD often have extensive atherosclerotic disease elsewhere and have a 1-year mortality rate as high as 20%, mainly from cardiovascular events. This case discussion briefly addresses the evidence for treating hypercholesterolemia in this subgroup of patients. Statins not only lower cholesterol, but also are antiinflammatory, antiproliferative, and antithrombogenic, and improve endothelial function. Current guidelines are reviewed and an approach to initiation of statins and their management is discussed.

References

Feb 19, 1998·The American Journal of Cardiology·T R PedersenT Haghfelt
Dec 4, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·P E LawsR A Fitridge
Sep 11, 2004·Journal of the American College of Cardiology·Scott M GrundyUNKNOWN Coordinating Committee of the National Cholesterol Education Program
Apr 25, 2006·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·A Gottsäter
Nov 11, 2008·The New England Journal of Medicine·Paul M RidkerUNKNOWN JUPITER Study Group
Jul 10, 2009·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·A H MomsenJ S Lindholt

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Citations

Aug 21, 2012·Vascular and Endovascular Surgery·Ralph G Depalma, Leo R Zacharski
Mar 21, 2015·Psychopharmacology·Joshua A HicksPhilip A Gable

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