Abstract
To determine the association between statin use and incident cataract surgery. Using the resources of the Rochester Epidemiology Project, a retrospective population-based, case-control study was performed. Cases included 6024 county residents aged 50 years and older who had first-eye cataract surgery between 1 January 2004 and 31 December 2011. Controls included residents who had never had cataract surgery and were matched to cases by age, sex, and index date within 1 month of surgery. Statin medications continuously prescribed for at least 1 year before the surgery date (cases) or index date (controls) were examined. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression models. There were 2557 (42%) statin users among cases having cataract surgery compared to 2038 (34%) statin users among controls never having had cataract surgery (p < 0.0001). Incident cataract surgery was significantly associated with increased odds of statin use (OR 1.29, 95% CI 1.19-1.55) after adjusting for age, sex, diabetes, cardiovascular disease, cerebrovascular disease, peripheral vascular disease, renal disease, oral and inhaled steroid use, and selective serotonin reuptake inhibitor use. The association was c...Continue Reading
References
Dec 1, 1990·Acta Ophthalmologica·B L Lundh, S E Nilsson
Jan 1, 1990·Experimental Eye Research·R J GersonD L Bokelman
Nov 1, 1995·The British Journal of Ophthalmology·M L HarrisR Collins
Jan 1, 1996·Survey of Ophthalmology·R J Cenedella
Jun 15, 1997·American Journal of Epidemiology·D T GrayK H Baratz
Sep 26, 2001·Archives of Internal Medicine·R G SchliengerC R Meier
Jul 27, 2002·Journal of the American College of Cardiology·Richard C PasternakUNKNOWN National Heart, Lung and Blood Institute
Apr 19, 2003·QJM : Monthly Journal of the Association of Physicians·L SmeethA E Fletcher
Feb 17, 2006·The European Respiratory Journal·P ErnstS Suissa
Jun 22, 2006·JAMA : the Journal of the American Medical Association·Barbara E K KleinLisa M Grady
Mar 28, 2007·American Journal of Ophthalmology·Jennifer S L TanJie Jin Wang
Jul 25, 2009·The British Journal of Ophthalmology·G L KanthanP Mitchell
Feb 4, 2010·Annals of Epidemiology·Gabriel ChodickVarda Shalev
Mar 9, 2010·Ophthalmology·Mahyar EtminanJames M Brophy
Mar 25, 2011·American Journal of Epidemiology·Jennifer L St SauverWalter A Rocca
Oct 11, 2011·American Journal of Ophthalmology·Donald S Fong, Kwun-Yee T Poon
Nov 15, 2011·BMC Ophthalmology·Carol J WaudbyCatherine A McCarty
Feb 7, 2012·Mayo Clinic Proceedings·Jennifer L St SauverWalter A Rocca
Apr 13, 2012·JAMA : the Journal of the American Medical Association·Rita F Redberg, Mitchell H Katz
Jul 17, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Carolyn M MachanElizabeth L Irving
Dec 4, 2012·Mayo Clinic Proceedings·Walter A RoccaL Joseph Melton
Jun 19, 2013·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Chao-Lun LaiMei-Shu Lai
Jun 25, 2013·Mayo Clinic Proceedings·Wenjun ZhongWalter A Rocca
Jul 4, 2013·Journal of Cataract and Refractive Surgery·Heidrun E GolloglyJay C Erie
Sep 21, 2013·JAMA Ophthalmology·Jessica LeuschenIshak Mansi
Feb 6, 2014·JAMA : the Journal of the American Medical Association·Victor M MontoriHenry H Ting
Mar 19, 2014·American Journal of Ophthalmology·Jay C ErieDavid O Hodge
Citations
Dec 6, 2016·Ophthalmic Epidemiology·Mohammed Dantani AdamuUNKNOWN Global Trachoma Mapping Project
Jul 12, 2018·Clinical Pharmacology and Therapeutics·Julien BezinAntoine Pariente
Mar 23, 2017·Journal of the American Heart Association·Shandong YuLin Wu
Jan 1, 2019·Cardiovascular Therapeutics·Carlos AlvesFrancisco Batel Marques
Jul 24, 2018·Current Vascular Pharmacology·S MohammadJ P Kitzmiller
Jan 15, 2019·Journal of Cataract and Refractive Surgery·Liyan LiuNeal H Shorstein
Jun 13, 2019·Scientific Reports·Damian M DaszynskiPeter F Kador
Mar 21, 2018·Eye·Ahmed Al-JanabiOren Tomkins-Netzer
Feb 24, 2016·Expert Opinion on Drug Safety·A KeiM S Elisaf
May 18, 2019·Nutrients·Justyna Widomska, Witold K Subczynski
Nov 19, 2020·BioMed Research International·Hidetoshi IshidaEri Kubo
Feb 2, 2019·Thérapie·Julien Bezin, Nicholas Moore
Nov 1, 2020·Experimental Eye Research·Raju TimsinaLaxman Mainali
Jul 3, 2021·Membranes·Raju Timsina, Laxman Mainali
Aug 6, 2021·The British Journal of Ophthalmology·Yixiong YuanMingguang He