Statins for Smith-Lemli-Opitz syndrome

The Cochrane Library
Rami A BalloutForbes D Porter

Abstract

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: 1. To evaluate the efficacy of statin therapy in reducing the frequency or severity of the neurobehavioral abnormalities seen in people with SLOS (e.g. aggression, anxiety, irritability, self-mutilation, autistic behaviors, sleep disturbances, etc.) (Wassif 2017). 2. To evaluate the potential effects of statin therapy on survival.

References

Sep 1, 1992·Journal of Personality and Social Psychology·A H Buss, M Perry
May 1, 1994·American Journal of Medical Genetics·M R Natowicz, J E Evans
Jan 31, 1997·American Journal of Medical Genetics·N A Nwokoro, J J Mulvihill
May 21, 1999·Lancet·T A Furukawa
May 12, 2000·Journal of Medical Genetics·R I Kelley, R C Hennekam
Feb 13, 2001·The British Journal of Dermatology·R M AzurdiaL E Rhodes
Feb 27, 2001·American Journal of Medical Genetics·E TierneyR I Kelley
Mar 27, 2002·International Journal of Epidemiology·Diana R ElbourneAndy Vail
Sep 10, 2002·Journal of the American Academy of Child and Adolescent Psychiatry
Oct 31, 2002·American Journal of Medical Genetics·Lena StarckIngemar Björkhem
Mar 26, 2003·Nature Genetics·Michael K CooperPhilip A Beachy
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Dec 8, 2004·American Journal of Medical Genetics. Part a·Massimiliano RossiGiancarlo Parenti
May 18, 2005·Molecular Genetics and Metabolism·Christopher A WassifForbes D Porter
May 15, 2007·Journal of Inherited Metabolic Disease·D HaasP Burgard
Feb 21, 2008·European Journal of Human Genetics : EJHG·Forbes D Porter
Dec 17, 2009·American Journal of Medical Genetics. Part a·Elaine TierneyForbes D Porter
Mar 10, 2010·Sub-cellular Biochemistry·Gesine Saher, Mikael Simons
Feb 12, 2011·BMJ : British Medical Journal·Richard D RileyJonathan J Deeks
Apr 15, 2011·Progress in Brain Research·Terry L JerniganKathrine Skak Madsen
Oct 13, 2011·American Journal of Medical Genetics. Part a·Simona E BianconiConstantine A Stratakis
Mar 23, 2012·American Journal of Medical Genetics. Part a·Małgorzata J M NowaczykJudith E Allanson
Oct 13, 2012·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Małgorzata J M Nowaczyk, Mira B Irons
Jan 16, 2013·European Journal of Pediatrics·Anna V OláhIstván Balogh
Jul 31, 2013·Biological Psychiatry·Zeljka KoradeNed A Porter
Nov 19, 2013·Journal of the American College of Cardiology·Neil J StoneUNKNOWN American College of Cardiology/American Heart Association Task Force on Practice Guidelines
Feb 18, 2014·Hereditary Genetics : Current Research·Steven J Fliesler
Dec 20, 2015·Human Molecular Genetics·Robert BlassbergJohn Jacob
Aug 12, 2016·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Christopher A WassifForbes D Porter
Oct 14, 2016·BMJ : British Medical Journal·Jonathan Ac SterneJulian Pt Higgins

❮ Previous
Next ❯

Citations

Aug 28, 2021·Balkan Journal of Medical Genetics : BJMG·N BegicE Begic

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Human Genetics : EJHG
Martina Witsch-BaumgartnerDorothea Haas
QJM : Monthly Journal of the Association of Physicians
B A GolombJ E Dimsdale
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
Andrea Diaz-Stransky, E Tierney
© 2021 Meta ULC. All rights reserved