Statistical analysis of 18 F-fluorodeoxyglucose positron-emission tomography/computed tomography ground-glass nodule findings

Molecular and Clinical Oncology
Kazuya NishiiMitsumasa Kaji

Abstract

18F-fluorodeoxyglucose positron-emission tomography/computed tomography (18F-FDG-PET/CT) is important in lung cancer diagnosis; false negatives are often caused by ground-glass nodules (GGNs). PET/CT utility in GGN diagnosis is unknown. The associations between GGN CT findings (size, properties), the pathological diagnosis and maximum standardized uptake value (SUVmax) were explored. Sixty-six patients with pathological stage IA1-IIA lung adenocarcinoma underwent surgical resection and PET/CT between January 2010 and December 2014. Clinical characteristics, CT findings, pathological diagnoses and PET/CT findings were retrospectively examined. The age range was 47-86 years (median, 69 years), the female/male ratio was 38:28 and the pathological stage was IA1, IA2, IA3, IB and IIA in 5, 30, 21, 9 and 1, respectively. Total and solid-part lesion diameters ranged from 7.00-41.13 mm (median, 19.43 mm) and 0.00-23.23 mm (median, 4.55 mm), respectively; the solid-part ratio (solid-part diameter/total diameter) was 0-77% (median, 20%). SUVmax ranged from a value too low for evaluation to 3.9 (median, 1.0). Pathological diagnoses were adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), lepidic-predominant adenocarcino...Continue Reading

References

Mar 17, 2001·JAMA : the Journal of the American Medical Association·M K GouldD K Owens
Jun 16, 2004·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Hiroaki NomoriKimiichi Uno
Feb 3, 2007·Current Opinion in Oncology·Johan Vansteenkiste, Christophe Dooms
Jan 22, 2009·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Eun Ju ChunChang Hyun Lee
Jan 22, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·William D TravisDavid Yankelewitz
Dec 24, 2011·AJR. American Journal of Roentgenology·Tae Jung KimKyung Won Lee
Sep 7, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Go AkamatsuMasayuki Sasaki
Aug 21, 2015·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·William D TravisUNKNOWN WHO Panel
Jan 15, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Peter GoldstrawUNKNOWN International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee Advisory Boards and Particip

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