PMID: 8969071Nov 1, 1996Paper

Statistical analysis of recovery from sudden deafness among treatment groups

Nihon Jibiinkoka Gakkai kaiho
Ken KitamuraT Kubo

Abstract

This study examined 131 patients with idiopathic sudden deafness in whom the averaged of five frequency hearing levels was greater than 60dB. Since combined pharmacotherapy has been used in the treatment of idiopathic sudden deafness, it is hard to make a quantitative analysis of single-drug efficacy. We used a single-drug treatment in turn to assess the drug efficacy within 30 days after the onset. There was no significant difference among patients treated within 6 days and not less than 7 days after the onset with steroid therapy, PGE1 therapy, and defibrinogenation therapy. Similarly, there was no significant difference among patients treated within 6 days and not less than 7 days after the onset with steroid and defibrinogenation combined therapy, steroid and PGE1 combined therapy, and steroid, defibrinogenation and Lasix-Vitamin combined therapy. In case of no steroid effect, treatment with defibrinogenation, PGE1 and Lasix-Vitamin therapy could achieve hearing improvement.

Citations

Jul 3, 2013·The Cochrane Database of Systematic Reviews·Benjamin P C WeiStephen O'Leary
Aug 28, 2003·The Annals of Otology, Rhinology, and Laryngology·Renzo MoraT J Yoo

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