PMID: 9644924Jun 30, 1998Paper

Statistical estimation of the precision of clinico-laboratory measurements

Klinicheskaia laboratornaia diagnostika
I S Balakhovskiĭ

Abstract

Traditionally, the term "precision" denotes the quality of work, uniting the correctness and reproducibility of results. However, it can have another sense: the minimal difference between the specimens, detectable by this or that device or method. In order to rule out misunderstanding, we propose to use the term "measuring precision", if the term is used in its second meaning. It is easy to assess the measuring precision by statistical processing of large scope of data: if the histogram shows waves which disappear after the histogram step is increased, this means that the device and method used in this study permit biochemical analysis only at measuring precision corresponding to the histogram step at which the waves disappear. A table of measuring precision values is offered for 19 methods realized using the Labsystems FP-900 device (Finland) In many cases it is obviously low.

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