PMID: 11343359May 9, 2001Paper

Statistical models appropriate for designs often used in group-randomized trials

Statistics in Medicine
D M Murray

Abstract

Group-randomized trials are characterised by the allocation of identifiable groups rather than individuals to study conditions; members within those groups are then observed to assess the effect of the intervention. It is convenient to categorize the designs employed in group-randomized trials along two dimensions, each with two levels. The first distinguishes between designs having just one or two time intervals and those having three or more intervals. The second distinguishes between nested cohort and nested cross-sectional designs. Following a brief review of the design and analytic issues common to group-randomized trials, and their general solutions, this paper presents the adaptations of the mixed-model analysis of covariance and random coefficients models that are required for the four combinations that result from this categorization scheme. The assumptions, strengths and weaknesses of each model are discussed.

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Citations

Jun 15, 2006·Prevention Science : the Official Journal of the Society for Prevention Research·Keith SmolkowskiJohn Seeley
Oct 24, 2003·Preventive Medicine·Stephen HavasCarlo DiClemente
Jul 15, 2004·Journal of Epidemiology and Community Health·Miguel Delgado-Rodríguez, Javier Llorca
Mar 4, 2009·Clinical Trials : Journal of the Society for Clinical Trials·Jeanne JacksonFlorence Clark
Mar 5, 2004·American Journal of Public Health·David M MurrayJonathan L Blitstein
Oct 31, 2009·Bulletin of the World Health Organization·David OsrinAnthony M Costello
Apr 11, 2012·American Journal of Health Behavior·Kimberly G WagonerMark Wolfson
Mar 19, 2008·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Russell E Glasgow
Apr 8, 2011·International Journal of Medical Informatics·Miriam McMullanSusan Lea
Aug 21, 2007·Preventive Veterinary Medicine·L K LordJ M Scarlett
Dec 25, 2016·Multivariate Behavioral Research·Daniel McNeish, Kathryn R Wentzel
Feb 6, 2003·Evaluation Review·David M Murray, Jonathan L Blistein
Mar 20, 2018·Preventive Medicine·David M MurrayShakira M Nelson

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