PMID: 11930189Apr 4, 2002Paper

Statistical parametric mapping in brain single photon computed emission tomography after carbon monoxide intoxication

Nuclear Medicine Communications
N WatanabeH Seto

Abstract

The purpose of this retrospective study was to assess regional cerebral blood flow in patients after carbon monoxide intoxication by using brain single photon emission computed tomography and statistical parametric mapping. Eight patients with delayed neuropsychiatric sequelae and ten patients with no neuropsychiatric symptoms after carbon monoxide intoxication were studied with brain single photon emission tomography imaging with 99mTc-hexamethyl-propyleneamine oxime. Forty-four control subjects were also studied. We used the adjusted regional cerebral blood flow images in relative flow distribution (normalization of global cerebral blood flow for each subject to 50 ml x 100 g(-1) x min(-1) with proportional scaling) to compare these groups with statistical parametric mapping. Using this technique, significantly decreased regional cerebral blood flow was noted extensively in the bilateral frontal lobes as well as the bilateral insula and a part of the right temporal lobe in the patients with delayed neuropsychiatric sequelae as compared with normal volunteers (P< 0.005). In the patients with no neuropsychiatric symptoms, significantly decreased regional blood flow in the bilateral frontal lobes particularly on the left side wa...Continue Reading

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Citations

Apr 18, 2006·Annals of Nuclear Medicine·Hulya Ortapamuk, Seniha Naldoken
Mar 18, 2008·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Gurayten OzyurtEray Alper
Mar 16, 2006·Brain Injury : [BI]·Ramona O HopkinsJohn F Foley
Jun 25, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Konosuke IwamotoYasuo Iwasaki
Aug 8, 2006·Behavioral and Cognitive Neuroscience Reviews·Ramona O Hopkins, Fu Lye M Woon

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